TY - JOUR ID - 21821 TI - The Effect of Eight Weeks of Endurance Training with Royal Jelly Consumption on Oxidant-Antioxidant Markers of the Left Ventricle of Orectomized Rats with Diabetes JO - Journal of Nutrition,Fasting and Health JA - JNFH LA - en SN - AU - Haq Panah Siasar, Behrooz AU - Abedi, Bahram AU - Hosseini, Seyed Ali AD - Department of Physical Education and Sports Sciences, Mahallat Branch, Islamic Azad University, Mahallat, Iran. AD - Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran. Y1 - 2023 PY - 2023 VL - 11 IS - 1 SP - 8 EP - 14 KW - Exercise KW - Royal jelly KW - Antioxidant KW - Left ventricle KW - Postmenopausal diabetes DO - 10.22038/jnfh.2023.69126.1412 N2 - Introduction: The simultaneous effect of endurance training (ET) and Royal Jelly (RJ) consumption on left ventricular oxidant-antioxidant markers as an important functional part of the heart is still not well known. Therefore, the aim of our study was to investigate the effect of eight weeks of ET and RJ on the levels of Superoxide Dismutase (SOD), Glutathione Peroxidase (GPx) and Malondialdehyde (MDA) in the left ventricle of orectomized rats with diabetes (OVXD). Methods: In this experimental study, 30 OVXD female rats aged 12-16 weeks and weighing 220-250 grams were divided into (1) OVXD control, (2) sham, (3) RJ, (4) ET and (5)ET+RJ groups. Also, 6 rats were included in the healthy control group (HC). Groups 4 and 5 trained five sessions a week with 55-75% of maximum running speed for eight weeks; Groups 3 and 5 received 100 mg/kg/day RJ by intraperitoneal injection. Results:  GPx and MDA values in RJ, ET and ET+RJ groups were significantly higher than OVXD group (P≤0.01). SOD levels in RJ groups were significantly higher than OVXD group (P≤0.01). Also, GPx values in RJ group were significantly higher than ET group (P≤0.01). Conclusion: It seems that ET and RJ can reduce lipid peroxidation in the left ventricle of the heart in OVXD rats. RJ administration either alone or simultaneously with ET can have antioxidant effects, but the effect of exercise depended on the duration of the exercise period. Therefore, RJ consumption along with sports exercise can be recommended in menopause and diabetes. UR - https://jnfh.mums.ac.ir/article_21821.html L1 - https://jnfh.mums.ac.ir/article_21821_9d3ceb6aeec17a6feb23e46fb3c1b9fd.pdf ER -