Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601Islamic Worldview, Fasting and Health1041061187710.22038/jnfh.2018.34765.1144ENAhmad SadatiDepartment of Sociology, Yazd University, Yazd, Iran0000-0001-5708-775Journal Article20180909Fasting effects on health and well-being. Although this effects were studied based on biological view, however there is a different view based on our Islamic teachings. Fasting is related to human virtues such as piety and cautious. These virtues are related to others characteristics in Islamic view which show the holistic view of Islam on health. In order to answer this question refer to Holy Qur’an which says in Chapter 2, Verse 183: ‘Believers, fasting is decreed for you as it was decreed for those before you; perchance you will be cautious’. As this verse shows fasting is related to piety and cautious. Here, the main function of fasting is not health but is another function which is piety. Therefore, fasting effects on health indirectly. As Fig.1 shows fasting alongside with other Muslim behavior such as attending Masque, daily Prayer, reading Qur'an, Devotion & Surrender, and Pilgrimage (HAJ) effect on several things. Human virtues such as forgiveness, honesty, self- discipline, altruism, generosity, humility, gratefulness, patience and dependability are affected by them. As we know these characteristics are important for being a healthy man. These items effect on all dimensions of health which are physical, psychological, social, and spiritual. Therefor piety leads to a features such as hope, contentment, patience and not being greedy. These characteristics leaded to our health and well-being generally. Theoretical and practical debates is recommended.Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601The Correlation between Glucose and Lipid Biomarkers Variations with Biometric Characteristics and Intraocular Pressure Changes during Ramadan Fasting84871184010.22038/jnfh.2018.34537.1142ENMohammad Reza SedaghatCornea Research Center, Khatam‐Al‐Anbia Hospital, Mashhad University of Medical Sciences, Mashhad, Iran0000-0001-8493-6241Nasrin Moghadas SharifRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Optometry, School of Paramedical Science, Mashhad University of Medical Sciences, Mashhad, IranFarshad AsgarizadehRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Optometry, School of Paramedical Science, Mashhad University of Medical Sciences, Mashhad, IranTahereh RakhshandadiRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Optometry, School of Paramedical Science, Mashhad University of Medical Sciences, Mashhad, IranJavad Heravian ShandizRefractive Errors Research Center, Department of Optometry, School of Paramedical Science, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-5785-3480Journal Article20180829<strong>Introduction: </strong>The aim of present study was to assess the correlation between glucose and lipid biomarkers variations with biometric characteristics and intraocular pressure changes following Ramadan fasting. <strong>Methods: </strong>A total of 100 healthy fasting volunteers were enrolled in the study. Of them, 89 subjects completed the study with respect to inclusion and exclusion criteria. Right eye ocular axial length and anterior chamber depth were determined using the IOLMaster, (Carl Zeiss Meditec, Jena, Germany). Following that, intraocular pressure of right eye was measured using a non-contact tonometer (Topcon, Computerized Tonometer CT-1/CT-1P, Tokyo, Japan). Blood samples were taken from all the participants and concentrations of the biomarkers, including Fast blood sugar, Triglyceride, Cholesterol, High-density lipoprotein and Low-density lipoprotein were measured using the Hitachi 717 analyzer (Hitachi, Tokyo, Japan). All assessments were obtained one week before and after Ramadan. <strong>Results: </strong>Of 89 healthy Muslims who complete the study, 51 were men (mean age: 35.51±8.94 years) and 38 were women mean age: 34.26±9.41 years).The results indicated no significant relationship between the axial length with glucose and lipid biomarkers variations in the fasting individuals. The assessment of result showed only a slight correlation between anterior chamber depth and High-density lipoprotein changes during Ramadan, however, this was not statistically significant. Also, findings revealed only a slight correlation between intraocular pressure and cholesterol changes in healthy fasting individuals, however, this was not statistically significant. <strong>Conclusion:</strong> Our study revealed that ocular parameters changes during Ramadan fasting is probably independent to variation levels of glucose and lipid biomarkers. Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601The Evaluation of Aflatoxin Contamination in Various Foods in Iran: a Review71831148510.22038/jnfh.2018.33536.1120ENMajid RamezaniDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000-0003-1045-1828Mohamad HashemiDepartment of Nutrition, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000-04525-A125-9874Asma AfshariDepartment of Nutrition, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-0915-8379Journal Article20180719<strong>Introduction:</strong> Aflatoxins are secondary fungal metabolites produced by <em>Aspergillus</em> <em>fung</em>i, in particular <em>Aspergillus flavus</em>, <em>Aspergillus nomius</em> and <em>Aspergillus parasiticus</em>. Aflatoxins have undesirable effects on human and animal health and lead to various diseases, including liver disorders. Four main types of aflatoxin are B1, B2, G1 and G2, and aflatoxin M1 and M2 are metabolites derived from aflatoxins B1 and B2. <strong>Materials and Methods:</strong> In this paper, studies on aflatoxin contamination in different foods were investigated. Keywords for related articles include: Aflatoxin, Iran, Incidence, Food, Oil, Milk and Dairy Products. Articles were obtained from SID, Science direct, PubMed and Google scholar databases. Abstract of all related articles were reviewed and finally, articles which mentioned to the amount of aflatoxin were selected.<strong>Results:</strong> Results showed the presence of aflatoxins in most of the tested food. In most studies conducted on milk and various dairy products, the level of aflatoxin was higher than the recommended level set by the Institute of Standards and Industrial Research of Iran and the European Union. <strong>Conclusion(s):</strong> Practical management and control strategies are necessary for assurance of the safety of consumers regarding aflatoxin residue in different foods in Iran.Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601Microbial Evaluation of Neutropenic Diet in Bone Marrow Transplant Department in Iran991031133610.22038/jnfh.2018.33224.1118ENMahsa TousiDepartment of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.0000-0001-5934-6207Abdolreza NorouzyAssociate Professor, Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.0000-0001-5934-6207Mohammad VaeziHematology-Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.Ali GhasemiAssociate professor of pediatric hematology and oncology, faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Maryam KhosraviDepartment of Nutrition, School of Medicine, Mashhad University of medical Sciences, Mashhad; and Department of Public Health, North Khorasan University of medical Sciences, Bojnurd, Iran.0000-0001-9708-5466Ardeshir GhavamzadeHematology-Oncology and SCT Research Center, Department of Hematology-Oncology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.Journal Article20180706<strong>Background:</strong> The use of a neutropenic diet after hematopoietic stem cell transplantation (HSCT) was instituted more than 30 years ago. This diet was targeted toward preventing from infection with organisms colonizing the gastrointestinal tract and the food-borne pathogens, which are the most important cause of illness and death in developing countries. Regarding this, the present study aimed to evaluate neutropenic diet in patients undergoing bone marrow transplantation in a selected hospital. This study also sought to investigate the role of hospital foods in the transmission of clinically important bacteria to the hospitalized patients. <strong>Materials and Methods:</strong> This cross-sectional study was conducted on the specimens of the foods served in the Bone Marrow Transplant Department of Shariati Hospital, Tehran, Iran. The samples were evaluated in terms of bacterial contamination using the standard method of American Public Health Association and Food and Drug Administration (FDA). <strong>Results:</strong> According to total bacteria and coliform counts, No contamination was detected in any of the tested specimens. <strong>Conclusion:</strong> As the findings indicated, the neutropenic diet, was found to be fully in line with the standards of the Ministry of Health and FDA both in terms of guidelines and food analysis.Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601A Comparative Study of Micronutrient Levels in the Women with Hypertensive Gestational Diabetes With and Without Preeclampsia1151211146110.22038/jnfh.2018.34329.1140ENFarideh AkhlaghiObstetrics&amp;Gynecology, Medical school, Mashhad University of Medical Sciences, Mashhad, Iran0000-0003-2014-8494Fatemeh MolkizadehResident of Obstetrics and Gynecology, Department of Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.0000-0002-6283-9480Journal Article20180821<strong>Introduction:</strong> Diabetes is a common metabolic disease during pregnancy. Preeclampsia is the most prevalent disorder that accompanies gestational diabetes. Recent studies have demonstrated the role of micronutrients in diabetic women with preeclampsia. The present study aimed to compare the levels of micronutrients in the women with gestational and hypertensive diabetes with and without preeclampsia. <strong>Methods:</strong> This descriptive study was conducted on 72 women with gestational and hypertensive diabetes with and without preeclampsia, who were in the third trimester of pregnancy. Demographic characteristics and data on the previous and current pregnancies were obtained using a questionnaire. In addition, blood samples were collected, and the levels of micronutrients were measured, including iron, zinc, magnesium, and lipid profile. Data analysis was performed in SPSS version 19 using t-test and Chi-square at the significance level of 0.05. <strong>Results:</strong> Among 72 participants, 32 cases had gestational diabetes and hypertension with preeclampsia, and 40 cases were without preeclampsia. Mean iron level in the group with preeclampsia was 108.91± 64.58, while it was 79.75±53.33 in the group without preeclampsia. The level of zinc in the group with preeclampsia was 65.73±24.40, while it was 53.17±19.23 in the group without preeclampsia. The level of copper in groups with and without preeclampsia was 220.59±61.92 and 192.83±47.46, respectively. Differences between the groups in terms of the levels of iron (P=0.39), zinc (P=0.02), and copper (P=0.035) were considered significant. In addition, the levels of magnesium, cholesterol, and triglyceride had no significant differences between the groups (P>0.5) <strong>Conclusion:</strong> According to the results, the levels of micronutrients such as iron, zinc, and copper were higher in the women with gestational and hypertensive diabetes with preeclampsia compared to those without preeclampsia.Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601Evaluating Persian Adoption of FDA Food Defense Assessment Checklist for Dairy Producing Units in Northeastern of Iran88981187610.22038/jnfh.2018.33169.1117ENAli BarzegarAssistant professor, School of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran0000-0003-0801-3714Mahbubeh AbdollahiAssistant Professor, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.0000-0001-8907-2745Abbas MalekMSc of Nutrition in Disaster, Student research committee, School of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran0000-0002-2334-0599Journal Article20180703<strong>Introduction:</strong> In today's world, “It is believed that use of microbial agents and biological toxins are harmful for human health. Food industry is a soft target and potentially vulnerable to deliberate contamination. The manufacturing units of dairy industry are a good example. The purpose of this study was to determine the level of food defense preparedness of dairy production units using FDA Food Defense Assessment Checklist. <strong>Methods:</strong> In this descriptive cross-sectional study<em>, </em><em>Persian</em>version of checklist was prepared using<em>backward</em><em>-</em><em>forward translation method</em> and evaluated for its face and content validity by the panel of experts. Content validity index (CVI) and content validity ratio (CVR) of all items were calculated. After the localization of the study tool, 39 dairy producers entered the study. <strong>Results:</strong> After modifying checklist based on validity assessment and localization, the number of questions reduced from 34 to 31. The level of food defense preparedness in dairy producers in terms of management, human element, facility, and operations were 38.3%, 45.5%, 67.7%, and 92.1% respectively. The only item in the checklist that was seen in all evaluated units was the existence of an initial assessment plan for the adequacy of food security procedures to prevent the deliberate contamination. <strong>Conclusion:</strong> The results of this study showed that food defense preparedness of large-scale dairy producers was not ideal and it was determined impractical in many items. Hence, further studies are required to determine its cause and then take the necessary steps to enhance the level of preparedness.Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601The Effect of Ethiopian Orthodox Christians ‘Abiy Tsom’ (Lent fasting) on Metabolic Syndrome Indices and Serum Electrolytes60701191910.22038/jnfh.2018.35602.1153ENChala KenenisaEdaeBiomedical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia0000-0002-1414-2742Maria DegefBiochemistry, Medicine, Addis Ababa University, Addis Ababa, EthiopiaTariku SisayDepartment of Physiology, School of Medicine, Addis Ababa University0000-0001-7546-3147Solomon GenetGebreBiochemistry, Medicine, Addis Ababa University, Addis Ababa, EthiopiaWondyefraw Mekonendepartment of medical physiology, College of Health Sciences, Addis Ababa UniversityDiresibachew HailePhysiology, Medicine, Addis Ababa University, Addis Ababa, EthiopiaJournal Article20181016<strong>Background:</strong> -Fasting, the voluntary abstention from all restricted foods, is a feature of many religions, and the putative health benefits have attracted both scientific and popular interest. There is no clear understanding that religious fasting has great effects on metabolic syndrome. There is little data available that provides information concerning Ethiopian Orthodox Christians fasting influence on metabolic syndrome indices and serum electrolytes to date. <strong>Objective:</strong> -To determine the effect of ‘Abiy tsom’ (lent fasting) of Ethiopian Orthodox Christians on metabolic syndrome indices and serum electrolytes in Addis Ababa, Ethiopia <strong>Methodology:</strong> - 88 Study subjects were included conveniently who were followers of Ethiopian Orthodox Christianity faith and fasting “lent” and longitudinal cross-sectional study design was employed. Data were collected twice, the first during last week of the fasting months and the second during the last week of two months’ time after returning to usual diet. The data and sample were collected, analyzed, interpreted and was displayed by using descriptive and analytical statistical methods. <strong>Results:</strong> Our study found that Ethiopian Orthodox lent fasting had clear and significant effects on Anthropometric measurements, systolic blood pressure, lipid profiles, and Urea. It was also found that this fasting decreased the levels of Calcium and Chloride ions while Serum sodium and potassium were influenced insignificantly. <strong>Conclusion:</strong> Ethiopian Orthodox Christians lent fasting is beneficial for weight loss and fighting metabolic syndrome.Mashhad University of Medical Sciences (MUMS)Journal of Nutrition,Fasting and Health2821-27466220180601Plasma Levels of Vascular Endothelial Growth Factor and Its Soluble Receptor in Non-alcoholic Fatty Liver Disease1071141200210.22038/jnfh.2018.33580.1124ENMahmoud Belghaisi-NaseriDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.0000-0002-6485-6655Zahra DehnaviDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000-0001-5934-6207Farkhonde RazmpourDepartment of Clinical Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranMahsa TousiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranAli TaghipourMashhad university of medical sciencesMohsen NematyDepartment of Nutrition, School of Medicine, Biochemistry and Nutrition, Endoscopic & Minimally Invasive Surgery, and Cancer Research Centers, Mashhad University of Medical Sciences (MUMS), Paradise Daneshgah, Azadi Square, Mashad, Iran0000-0003-3202-2709Ali BahariGastroenterology and Hepatology Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Mohsen Azimi-NezhadDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000000000000000Journal Article20180721<strong>Introduction: </strong>Non-alcoholic fatty liver disease (NAFLD) is a clinical pathologic condition, which leads to inflammation events in hepatocytes. The objective of present study was to compare the plasma levels of VEGF and sVEGFR-1 as inflammation factors in overweight and obese children and adolescents with and without NAFLD. <strong>Materials and Methods: </strong>A total sample of 70 overweight and obese children and adolescents (37 boys and 33 girls) were recruited from those admitted to a nutrition clinic in Mashhad, northeastern Iran. The presence of NAFLD was determined by FibroScan, ultrasound and elevation of liver enzyme. Plasma VEGF and sVEGFR1 were also determined for each individual. <strong>Results: </strong>VEGF levels (log transformed) showed a significant stepwise increase from “zero” to “first”, “second” and “third” grades (P trend<0.001). However, sVEGFR1 (log transformed) did not show a regular trend between different grades of NAFLD (P trend=0.3). The odds ratios (95% confidence interval) for VEGF across categories of NAFLD were 1.00, 0.99 (0.97-1.01), 1.02 (0.99-1.04), and 1.04 (1.02-1.06). The odds ratios remained relatively unchanged even after adjusting for sex, age and BMI. <strong>Conclusion: </strong>This study showed a significant positive association between plasma VEGF levels and grades of steatosis in overweight and obese children and adolescents, even after adjustment for age, sex and BMI.