Association between Bariatric Surgery and Major Adverse Diabetes Outcomes in Patients with Diabetes and Obesity: A Systematic Review

Document Type : Review Article

Authors

1 Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Department of Internal Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Department of Trauma and General Surgery, Zahedan University of Medical Science, Zahedan, Iran.

6 Endocrine Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction: While significant randomized clinical trials have demonstrated the efficacy of bariatric surgery in the treatment of type 2 diabetes, there remains a notable gap in research exploring the potential risks associated with this procedure in patients with both diabetes and obesity. Despite the compelling evidence of its benefits, the associated risks and mortality outcomes specific to this patient population have not been extensively investigated. To better understand the relationship between bariatric surgery and these potential risks, as well as mortality among individuals with type 2 diabetes, comprehensive observational studies are essential. Method: This systematic review was conducted following the PRISMA guidelines for article selection. Relevant articles were identified by searching keywords related to bariatric surgery, metabolic surgery, diabetes, and type 2 diabetes. These keywords were combined and searched across databases including Google Scholar, PubMed, and ScienceDirect, in accordance with the inclusion and exclusion criteria. A total of 4 articles met the criteria and were included in the final analysis. Result: Among the 4 articles related to bariatric surgery and adverse diabetes outcomes in patients with diabetes and obesity, it can be concluded that although bariatric surgery offers many advantages, including a significant reduction in blood glucose levels and the achievement of stable glycemic control, it also has certain disadvantages. Conclusion: Although bariatric surgery offers many benefits, it also presents significant risks for patients with diabetes and a BMI of 35 or higher. These risks may lead to various complications, including worsening of diabetic retinopathy and severe hypoglycemia.

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Main Subjects

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Journal of Nutrition,Fasting and Health
Volume 13, Issue 2
June 2025
Pages 125-132

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History

  • Receive Date: 25 July 2024
  • Revise Date: 18 September 2024
  • Accept Date: 18 September 2024

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