The Effect of Ramadan Fasting on Lipid Profile in Pregnant Women

Document Type : Research Paper

Authors

1 Associate Professor, Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

2 Associate Professor, Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

3 Assistant Professor, Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran

4 Ph.D Student, Department of Parasitology and Mycology, Kerman University of Medical Sciences, Kerman, Iran

5 Associate Professor, Department of Epidemiology and Biostatistics, Shahrekord University of Medical Sciences, Shahrekord, Iran

Abstract

Introduction: Abnormal lipid profile causes maternal mortality and impairs fetal development. This study investigated the effect of Ramadan fasting on plasma lipid profile in pregnant women. Methods: This self-control, cohort study was performed in healthy volunteer fasted pregnant women. Serum cholesterol, triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), and body mass index (BMI) were measured on 0, 7th, 14th, and 28th days of Ramadan, and two weeks after Ramadan. Statistical analysis was performed by SPSS. Results: The mean age and BMI of participants was 26.9±6.4 year and 25±4.2 kg/m respectively. Weight and BMI of women did not change during the study. Cholesterol and LDL significantly increased during Ramadan and decreased after Ramadan (p

Keywords

References

  1. Robinson T, Raisler J. "Each one is a doctor for herself": Ramadan fasting among pregnant Muslim women in the United States. Ethn Dis. 2005;15(1 Suppl 1):S1-99-103.
  2. Joosoph J, Abu J, Yu SL. A survey of fasting during pregnancy. Singapore Med J. 2004;45(12):583-6.
  3. Arab M, Nasrollahi S. Interrelation of Ramadan fasting and birth weight. Med J Islamic Academy Sci. 2001;14(3):91-5.
  4. Janesick A, Blumberg B. Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity. Birth Defects Res C Embryo Today. 2011;93(1):34-50.
  5. Jamil AAT, Elsoni B, Zaki H, Elbadawi NEE, Ahmed EG, Ibrahim EK, et al. Assessment of lipid profile in sudanese pregnant women. Key Res J Biotechnol. 2013;1(1):4-15.
  6. Akturk I, Biyik I, Kocas C, Yalcin A, Erturk M, Uzun F. PP-106 Effects of Ramadan fasting on lipid profile, brain nadriuretic peptide, renal functions and electrolyte levels in patients with hypertension. Int J Cardiol. 2012;155:S134.
  7. Khafaji HA, Bener A, Osman M, Al Merri A, Al Suwaidi J. The impact of diurnal fasting during Ramadan on the lipid profile, hs-CRP, and serum leptin in stable cardiac patients. Vasc Health Risk Manag. 2012;8:7-14.
  8. Adlouni A, Ghalim N, Benslimane A, Lecerf JM, Saile R. Fasting during Ramadan induces a marked increase in high-density lipoprotein cholesterol and decrease in low-density lipoprotein cholesterol. Ann Nutr Metab. 1997;41(4):242-9.
  9. Waterhouse J, Alkib L, Reilly T. Effects of Ramadan upon fluid and food intake, fatigue, and physical, mental, and social activities: a comparison between the UK and Libya. Chronobiol Int. 2008;25(5):697-724.
  10. Akaberi A, Golshan A, Moojdekanloo M, Hashemian M. Does fasting in Ramadan ameliorate Lipid profile? A prospective observational study. Pak J Med Sci. 2014;30(4):708-11.
  11. Ziaee V, Razaei M, Ahmadinejad Z, Shaikh H, Yousefi R, Yarmohammadi L, et al. The changes of metabolic profile and weight during Ramadan fasting. Singapore Med J. 2006;47(5):409-14.
  12. Saleh SA, El-Kemery TA, Farrag KA, Badawy MR, Sarkis NN, Soliman FS, et al. Ramadan fasting: relation to atherogenic risk among obese Muslims. J Egypt Public Health Assoc. 2004;79(5-6):461-83.
  13. Frost G, Pirani S. Meal frequency and nutritional intake during Ramadan: a pilot study. Hum Nutr Appl Nutr. 1987;41(1):47-50.
  14. Framarino-dei-Malatesta M, Derme M, Napoli A, Iaria G, Manzia TM, Orlando G, et al. Placental, lipid, and glucidic effects of mammalian target of rapamycin inhibitors: impact on fetal growth and metabolic disorders during pregnancy after solid organ transplantation. Transplant Proc. 2014;46(7):2254-8.
  15. Srisawasdi P, Chaloeysup S, Teerajetgul Y, Pocathikorn A, Sukasem C, Vanavanan S, et al. Estimation of plasma small dense LDL cholesterol from classic lipid measures. Am J Clin Pathol. 2011;136(1):20-9.
  16. Maislos M, Khamaysi N, Assali A, Abou-Rabiah Y, Zvili I, Shany S. Marked increase in plasma highdensity- lipoprotein cholesterol after prolonged fasting during Ramadan. Am J Clin Nutr. 1993;57(5):640-2.
  17. Lamine F, Bouguerra R, Jabrane J, Marrakchi Z, Ben Rayana MC, Ben Slama C, et al. Food intake and high density lipoprotein cholesterol levels changes during ramadan fasting in healthy young subjects. Tunis Med. 2006;84(10):647-50.
  18. Bener A, Yousafzai MT. Effect of Ramadan fasting on diabetes mellitus: a population-based study in Qatar. J Egypt Public Health Assoc. 2014;89(2):47- 52.
  19. Norouzy A, Salehi M, Philippou E, Arabi H, Shiva F, Mehrnoosh S, et al. Effect of fasting in Ramadan on body composition and nutritional intake: a prospective study. J Hum Nutr Diet. 2013;26 Suppl 1:97-104.
  20. Ozturk E, Balat O, Ugur MG, Yazicioglu C, Pence S, Erel O, et al. Effect of Ramadan fasting on maternal oxidative stress during the second trimester: a preliminary study. J Obstet Gynaecol Res. 2011;37(7):729-33.
  21. Leiper J, Molla A. Effects on health of fluid restriction during fasting in Ramadan. Eur J Clin Nutr. 2003;57:S30-S8.
  22. Rolfes SR, Pinna K, Whitney E. Understanding normal and clinical nutrition. 7th ed. Thomson wadsworth: Cengage Learning; 2006.
  23. Gharbi M, Akrout M, Zouari B. [Food intake during and outside Ramadan]. East Mediterr Health J. 2003;9(1-2):131-40.
  24. Bakhotmah BA. The puzzle of self-reported weight gain in a month of fasting (Ramadan) among a cohort of Saudi families in Jeddah, Western Saudi Arabia. Nutr J. 2011;10:84.
  25. Hobel C, Culhane J. Role of psychosocial and nutritional stress on poor pregnancy outcome. J Nutr. 2003;133(5 Suppl 2):1709S-17S.
  26. Siega-Riz AM, Herrmann TS, Savitz DA, Thorp JM. Frequency of eating during pregnancy and its effect on preterm delivery. Am J Epidemiol. 2001;153(7):647-52.
  27. Hobel C, Siega-Riz A. The West Los Angeles preterm birth prevention project: a reassessment of interventions. J Matern Fetal Neonatal Med. 1998;3(1):161-4.
  28. Herrmann TS, Siega-Riz AM, Hobel CJ, Aurora C, Dunkel-Schetter C. Prolonged periods without food intake during pregnancy increase risk for elevated maternal corticotropin-releasing hormone concentrations. Am J Obstet Gynecol . 2001;185(2):403-12.
  29. Akaberi A, Golshan A, Moojdekanloo M, Hashemian M. Does fasting in Ramadan ameliorate Lipid profile? A prospective observational study. Pakistan J Med Sci. 2014;30(4):708.
  30. Brizzi P, Tonolo G, Esposito F, Puddu L, Dessole S, Maioli M, et al. Lipoprotein metabolism during normal pregnancy. Am J Obstet Gynecol . 1999;181(2):430-4.
  31. Napoli C, Witztum JL, Calara F, de Nigris F, Palinski W. Maternal hypercholesterolemia enhances atherogenesis in normocholesterolemic rabbits, which is inhibited by antioxidant or lipidlowering intervention during pregnancy: an experimental model of atherogenic mechanisms in human fetuses. Circ Res. 2000;87(10):946-52.
  32. Dutta D. Hypertensive disorders in pregnancy. Textbook of Obstetrics, Ed Konar, HL, 5th edition, New Central Book Agency, Kolkata. 2001:234-55.
  33. Obed S, Patience A. Birth weight and ponderal index in pre-eclampsia: a comparative study. Ghana Med J. 2006;40(1):8-13.
  34. Cross JH, Eminson J, Wharton BA. Ramadan and birth weight at full term in Asian Moslem pregnant women in Birmingham. Arch Dis Child. 1990;65(10 Spec No):1053-6.
  35. Dikensoy E, Balat O, Cebesoy B, Ozkur A, Cicek H, Can G. The effect of Ramadan fasting on maternal serum lipids, cortisol levels and fetal development. Arch Gynecol Obstet. 2009;279(2):119-23.
  36. Dimitrova-Sumkovska J, Dosic-Markovska B, Zafirova-Roganovic D, Anastasovska V. Effects of different dietary fatty acid supplements upon lipoprotein metabolism and lipid peroxides production in hyperlipidemic rats. Prilozi. 2006;27(1):67-86.
  37. Demirci O, Tugrul AS, Dolgun N, Sozen H, Eren S. Serum lipids level assessed in early pregnancy and risk of pre-eclampsia. J Obstet Gynaecol Res. 2011;37(10):1427-32.
  38. Ross R. Atherosclerosis is an inflammatory disease. Am Heart J. 1999;138(5):S419-S20.

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History

  • Receive Date: 28 July 2015
  • Revise Date: 05 August 2015
  • Accept Date: 05 August 2015

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