Meat Borne Parasites in Iran: A Review

Document Type : Review Article

Authors

1 Student of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran

2 Department of Clinical Sciences, Karaj Branch, Islamic Azad University, Karaj, Iran.

3 Department of Animal and Poultry Health and Nutrition,Faculty of Veterinary Medicine,University ofTehran,Tehran ,Iran. Institute of Biomedical Research, University of Tehran, Tehran, Iran

4 Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Zoonotic diseases transmitted from meat and its products are global significant issues in public health and the economy. A major factor in carcass condemnation in slaughterhouses is parasitic infections, which can have a severe negative effect on human societies' health. Parasites transmitted from red meat and its products and the induced disorders in humans include helminths such as Taenia spp. (intestinal disorders), liver flukes (hepatic disorders), and Trichinella spp. (intestinal and muscular disorders), as well as protozoans such as Toxoplasma gondii (neurological and reproductive disorders) and Sarcocystis spp. (gastrointestinal, respiratory, and muscle disorders) and Cryptosporidium spp. (intestinal disorders and severe diarrhea). In general, there is little knowledge about meat-borne parasitic diseases. Global food trade, population growth, unprincipled cooking methods, and lack of improvement in monitoring and diagnostic procedures are among the factors of increasing diagnostic cases of parasitic diseases caused by meat and meat products around the world, including Iran. Despite the decrease in meat consumption per capita in recent years, there is a significant prevalence of meat-borne parasitic diseases in the population of Iran, which requires attention towards preventive and monitoring methods. Northern Iran, including the provinces of Gilan and Mazandaran, has the greatest documented incidence of parasite illnesses in meat, especially in rural areas with humid climates where cattle are grown. Recent studies have estimated the prevalence of human infections in Iran. The studied diseases included taeniasis (0.25%-0 5%), trichinellosis (2.6% in high-risk group), fascioliasis (0.7% in Jolfa county), dicrocoeliasis (2.2% in Meshkinshahr city), toxoplasmosis (39.3% of the whole Iranian population), sarcocystosis (0.16%-0.1%, only found in 8 cases), cryptosporidiosis (2.9% of healthy population and 1.3% of patients suffering from gastroenteritis). This study aimed to evaluate the essential parasitic diseases transmitted through meat and meat products in the geographical area of Iran and their effects on both human and animal health.

Keywords

Main Subjects

References

  1. Augendre L, Costa D, Escotte-Binet S, Aubert D, Villena I, Dumètre A, et al. Surrogates of foodborne and waterborne protozoan parasites: A review. Food and Waterborne Parasitology. 2023:e00212.
  2. Torgerson PR, Devleesschauwer B, Praet N, Speybroeck N, Willingham AL, Kasuga F, et al. World Health Organization estimates of the global and regional disease burden of 11 foodborne parasitic diseases, 2010: a data synthesis. PLoS medicine. 2015;12(12):e1001920.
  3. Uslu U, Şenlik B. MEATBORNE PARASITIC ZOONOSIS. VETERINARY PATHOBIOLOGY & PUBLIC HEALTH. 2021:96.
  4. Di Bari C, Venkateswaran N, Fastl C, Gabriël S, Grace D, Havelaar AH, et al. The global burden of neglected zoonotic diseases: Current state of evidence. One Health. 2023:100595.
  5. Dorny P, Praet N, Deckers N, Gabriël S. Emerging food-borne parasites. Veterinary parasitology. 2009;163(3):196-206.
  6. Abuseir S. Meat-borne parasites in the Arab world: a review in a One Health perspective. Parasitology Research. 2021;120(12):4153-66.
  7. Khalkhali H, Foroutan M, Khademvatan S, Majidiani H, Aryamand S, Khezri P, et al. Prevalence of cystic echinococcosis in Iran: a systematic review and meta-analysis. Journal of helminthology. 2018;92(3):260-8.
  8. Pourmokhtar E, Moghaddasi R, Nejad AM, Hosseini SS. Meat demand model in Iran: A restricted source-differentiated almost ideal demand system approach. Economic Journal of Emerging Markets. 2018:194-204.
  9. Moazeni M, Khamesipour F, Anyona DN, Dida GO. Epidemiology of taeniosis, cysticercosis and trichinellosis in Iran: A systematic review. Zoonoses and public health. 2019;66(1):140-54.
  10. Nezamabadi M, Mashkour M, Aali A, Stöllner T, Le Bailly M. Identification of Taenia sp. in a natural human mummy (third century BC) from the Chehrabad salt mine in Iran. The Journal of parasitology. 2013;99(3):570-2.
  11. Saravi KH, Fakhar M, Nematian J, Ghasemi M. Co-infection with Enterobius vermicularis and Taenia saginata mimicking acute appendicitis. Journal of infection and public health. 2016;9(4):519-22.
  12. Faraji R, Nazari N, Negahdary M. Prevalence of cysticercus of Taenia saginata in cattle slaughtered. International Journal of Research in Medical Sciences. 2015;3(7):1662-5.
  13. Torgerson PR, Abdybekova AM, Minbaeva G, Shapiyeva Z, Thomas LF, Dermauw V, et al. Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in central and western Asia and the Caucasus. Parasites & vectors. 2019;12:1-8.
  14. Gholami N, Mosayebi M, Dehghan Rahim Abadi P, Rasmi Atigh H, Sedaghat R, Naji Zadeh MH, et al. Bovine cysticercosis in feedlot cattle in central region of Iran. Journal of parasitic diseases. 2020;44:25-30.
  15. Hosseinzadeh S, Setayesh A, Shekarforoush S, Fariman S. An epidemiological survey on the determination of Taenia saginata cysticercosis in Iran, using a PCR assay. Veterinary Record. 2013;172(17):451-.
  16. Khedri J, Radfar MH, Nikbakht B, Zahedi R, Hosseini M, Azizzadeh M, et al. Parasitic causes of meat and organs in cattle at four slaughterhouses in Sistan‐Baluchestan Province, Southeastern Iran between 2008 and 2016. Veterinary Medicine and Science. 2021;7(4):1230-6.
  17. Oryan A, Moghaddar N, Gaur S. Taenia saginata cysticercosis in cattle with special reference to its prevalence, pathogenesis and economic implications in Fars Province of Iran. Veterinary Parasitology. 1995;57(4):319-27.
  18. Nasiri V, Esmailnia K, Karim G, Nasir M, Akhavan O. Intestinal parasitic infections among inhabitants of Karaj City, Tehran province, Iran in 2006-2008. The Korean journal of parasitology. 2009;47(3):265.
  19. Kia E, Masoud J, Yalda A, Mahmoudi M, Farahani H. Study on human taeniasis by administring anti-taenia drug. Iranian Journal of Public Health. 2005;34(4):47-50.
  20. Kia E, Afshar-Moghadam N, Kazemzade H. Appendicular taeniasis: association with acute gangrene appendicitis in Isfahan, Iran. South Asian J Trop Med Public Health. 2004;35:259-61.
  21. Heidari A, Kalantar E, Fallah P, Dehghan MH, Saedi S, Sezavar M, et al. Case Record of a Teaching Hospital in Karaj; A 35-Year Old Man With Taenia saginata Infection Treated With Niclosamide. International Journal of Enteric Pathogens. 2016;4(4):9-37109.
  22. Bahreh M, Hajimohammadi B, Eslami G. Toxoplasma gondii in sheep and goats from Central Iran. BMC Research Notes. 2021;14:1-5.
  23. Borhani M, Fathi S, Harandi MF, Simsek S, Ahmed H, Wu X, et al. Trichinella infections in animals and humans of Iran and Turkey. Frontiers in Medicine. 2023;10:1088507.
  24. Koohsar F, Naddaf SR, Rokni MB, Mirjalali H, Mohebali M, Shafiei R, et al. Serological detection of trichinellosis among suspected wild boar meat consumers in North and Northeast of Iran. Iranian Journal of Parasitology. 2021;16(2):253.
  25. Eslahi AV, KarimiPourSaryazdi A, Olfatifar M, de Carvalho LMM, Foroutan M, Karim MR, et al. Global prevalence of Trichinella in pigs: A systematic review and meta‐analysis. Veterinary Medicine and Science. 2022;8(6):2466-81.
  26. Rostami A, Khazan H, Kia EB, Bandehpour M, Mowlavi G, Kazemi B, et al. Molecular identification of Trichinella spp. in wild boar, and serological survey of high-risk populations in Iran. Food Control. 2018;90:40-7.
  27. Franssen F, Swart A, van der Giessen J, Havelaar A, Takumi K. Parasite to patient: A quantitative risk model for Trichinella spp. in pork and wild boar meat. International journal of food microbiology. 2017;241:262-75.
  28. Afshar A, Jahfarzadeh Z. Trichinosis in Iran. Annals of Tropical Medicine & Parasitology. 1967;61(3):349-51.
  29. Rostami A, Riahi SM, Ghadimi R, Hanifehpour H, Hamidi F, Khazan H, et al. A systematic review and meta-analysis on the global seroprevalence of Trichinella infection among wild boars. Food Control. 2018;91:404-11.
  30. Kia E, Meamar A, Zahabiun F, Soodbaksh A, Kordbacheh P. An outbreak of human trichinellosis due to consumption of boar meat infected with Trichinella sp. Iran J Infect Dis Trop Med. 2008;41:35-8.
  31. Arbabi M, Talari SA. The prevalence of Toxoplasmosis in subjects involved in meat industry and pregnant women in Kashan. Feyz Medical Sciences Journal. 2002;6(2):28-38.
  32. Saadatnia A, Solhjoo K, Davami MH, Raeghi S, Abolghazi A. Molecular identification of Fasciola isolated from the liver of meat animals in Fars Province, Iran. Journal of parasitology research. 2022;2022(1):4291230.
  33. Mahami-Oskouei M, Forouzandeh-Moghadam M, Rokni MB. Prevalence and severity of animal Fasciolosis in six provinces of Iran. Feyz Medical Sciences Journal. 2012;16(3):254-60.
  34. Hatami H, Asmar M, Masoud J, Mansouri F, Namdaritabar H, Ramazankhani A. The first epidemic and new-emerging human fascioliasis in Kermanshah (western Iran) and a ten-year follow up, 1998-2008. International journal of preventive medicine. 2012;3(4):266.
  35. Moghadami M, Mardani M. Fasciola hepatica: a cause of obstructive jaundice in an elderly man from Iran. Saudi Journal of Gastroenterology. 2008;14(4):208-10.
  36. Lu X-T, Gu Q-Y, Limpanont Y, Song L-G, Wu Z-D, Okanurak K, et al. Snail-borne parasitic diseases: an update on global epidemiological distribution, transmission interruption and control methods. Infectious diseases of poverty. 2018;7:1-16.
  37. Khademvatan S, Majidiani H, Khalkhali H, Taghipour A, Asadi N, Yousefi E. Prevalence of fasciolosis in livestock and humans: a systematic review and meta-analysis in Iran. Comparative immunology, microbiology and infectious diseases. 2019;65:116-23.
  38. Eshrati B, Mokhayeri H, Rokni MB, Kheirandish F, Mafi M, Mokhayeri A, et al. Seroepidemiology of human fascioliasis in rural and nomad areas of Lorestan Province, western Iran, in 2016 and 2017. Journal of Parasitic Diseases. 2020;44:806-12.
  39. Amiri S, Shemshadi B, Sh F, Shirali S. Detection of Fasciola hepatica in lori sheep using polymerase Chain reaction and conventional diagnostic methods in Western Iran. Archives of Razi Institute. 2021;76(2):223.
  40. Radfar MH, Nourollahi-Fard SR, Mohammadyari N. Bovine fasciolosis: prevalence, relationship between faecal egg count and worm burden and its economic impact due to liver condemnation at Rudsar abattoir, Northern Iran. Journal of parasitic diseases. 2015;39:522-5.
  41. Zeinali S, Jafari R, Khademvatan S, Sakhaei G, Masudi S, Khashaveh S, et al. Seroprevalence of Fasciola sp. and Toxoplasma gondii Infections in Rural and Urban Inhabitants of Jolfa County, Northwest Iran. Journal of Parasitology Research. 2024;2024(1):5690707.
  42. Galavani H, Haniloo A, Raeghi S, Ghatee MA, Karamian M. Bioclimatic analysis and spatial distribution of fascioliasis causative agents by assessment of Lymnaeidae snails in northwestern provinces of Iran. Parasites & Vectors. 2024;17(1):244.
  43. Heydarian P, Ashrafi K, Esboei BR, Mehdi M-B, Kia EB, Aryaeipour M, et al. Emerging cases of fascioliasis in Lorestan Province, Western Iran: case Series report. Iranian Journal of Public Health. 2021;50(1):195.
  44. Asadi P, Zarei Z, Mohebali M, Alizadeh Z, Najafi F, Izadi S, et al. Intestinal Parasitic Infections in People Referring to the Central Laboratory of Meshkin Shahr County, Ardabil Province, Iran. Iranian Journal of Parasitology. 2024;19(1):105.
  45. Javanmard E, Mohammad Rahimi H, Nemati S, Soleimani Jevinani S, Mirjalali H. Molecular analysis of internal transcribed spacer 2 of Dicrocoelium dendriticum isolated from cattle, sheep, and goat in Iran. BMC Veterinary Research. 2022;18(1):283.
  46. Shokouhi S, Mirzaei A, Naserifar R, Abdi J. Dicrocoelium dendriticum infection among livestock in western Iran. 2018.
  47. Bari S, Sarvi S, Daryani A, Ziaeei Hezarjaribi H, Arbabi M, Pirestani M, et al. Dicrocoelium dentriticum infection among domestic animals in iran: A systematic review and meta-analysis. Journal of Mazandaran University of Medical Sciences. 2016;25(132):367-75.
  48. Hajipour N, Valizadeh H, Hassanzadeh P. Study on the role of age, sex and season on the prevalence of fascioliasis and dicrocoeliasis in animals slaughtered in Tabriz slaughterhouse. 2021.
  49. Mohammadi Dehcheshmeh F. A survey on prevalence and morphometric and molecular characterization of Dicrocoelium dendriticum in ruminants slaughtered in Eslamabad-e Gharb slaughterhouse. Veterinary Research & Biological Products. 2021;34(1):46-54.
  50. Gharekhani J, Yakhchali M. Risk factors associated to Toxoplasma gondii infection in dairy farms in Hamedan suburb, Iran. Journal of parasitic diseases. 2020;44(1):116-21.
  51. Yousefvand A, Mirhosseini SA, Ghorbani M, Mohammadzadeh T, Moghaddam MM, Mohammadyari S. Molecular and serological detection and of Toxoplasma gondii in small ruminants of southwest Iran and the potential risks for consumers. Journal of Consumer Protection and Food Safety. 2021;16:117-27.
  52. Foroutan M, Dalvand S, Daryani A, Ahmadpour E, Majidiani H, Khademvatan S, et al. Rolling up the pieces of a puzzle: a systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran. Alexandria journal of medicine. 2018;54(3):189-96.
  53. Daryani A, Sarvi S, Aarabi M, Mizani A, Ahmadpour E, Shokri A, et al. Seroprevalence of Toxoplasma gondii in the Iranian general population: a systematic review and meta-analysis. Acta tropica. 2014;137:185-94.
  54. Foroutan M, Majidiani H, Hassanipour S, Badri M. Toxoplasma gondii seroprevalence in the Iranian blood donors: A systematic review and meta-analysis. Heliyon. 2024.
  55. Mohammadi A, Shojaee S, Salimi M, Zareei M, Mohebali M, Keshavarz H. Seroepidemiological study of toxoplasmosis in women referred to arak marriage consulting center during 2012–2013. Iranian Journal of Public Health. 2015;44(5):654.
  56. Bashour N, Aminpour A, Vazifehkhah S, Jafari R. Seromolecular study on the prevalence and risk factors of Toxoplasma gondii infection in pregnant women referred to a gynecology hospital in Urmia, northwest part of Iran in 2022. BMC Infectious Diseases. 2024;24(1):410.
  57. Barzgar G, Ahmadpour E, Kohansal MH, Moghaddam SM, Koshki TJ, Barac A, et al. Seroprevalence and risk factors of Toxoplasma gondii infection among pregnant women. The Journal of Infection in Developing Countries. 2024;18(01):60-5.
  58. Sharif M, Sarvi S, Shokri A, Hosseini Teshnizi S, Rahimi M, Mizani A, et al. Toxoplasma gondii infection among sheep and goats in Iran: a systematic review and meta-analysis. Parasitology research. 2015;114:1-16.
  59. Pour HHL, Tavalla M, Valian HK, Mohebali M, Hafshejani SH, Latifi A, et al. Molecular Detection of Toxoplasma gondii Oocytes in Soil Samples from Guilan Province, Northern Iran. Iranian Journal of Public Health. 2024.
  60. Hooshyar MJ, Karimi A, Zarei P, Ghahremani A. Investigating the infection rate of Sarcocystis in hamburgers sold in Shiraz City, Iran. Journal of Alternative Veterinary Medicine| Spring. 2023;6(16).
  61. Dehkordi ZS, Yalameha B, Sari AA. Prevalence of Sarcocystis infection in processed meat products by using digestion and impression smear methods in Hamedan, Iran. Comparative clinical pathology. 2017;26:1023-6.
  62. Monazzah-harsini S. A review of the infection of domestic animals and humans with Sarcocystis parasites. 2019.
  63. Agholi M, Goodarzi A, Taghinezhad A. The present status of Sarcocystis spp. and sarcocystosis in Iran: a literature review. Annals of Parasitology. 2021;67(4).
  64. Ghazaei C. Evaluation of Sarcocyst Parasite Strains in Carcasses Obtained from Ardabil Meat Industrial Group. International Journal of Molecular and Clinical Microbiology. 2018;8(1):950-6.
  65. Hooshyar H, AbbasZadeh Z, Sherafati R, Arbabi M, Mousavi GA. Identification of Sarcocystis in raw hamburgers in Kashan, Iran. Journal of Food Microbiology. 2016;3(3):37-44.
  66. Hooshyar H, Akhavan Taheri M, Mazoochi T, Shahabi Ghahfarokhi B. Prevalence of Sarcocystis spp. in Meat-producing Ruminants in Kashan, Central Iran. Nigerian Journal of Parasitology. 2024;45(1).
  67. Nourollahi Fard SR, Asghari M, Nouri F. Survey of Sarcocystis infection in slaughtered cattle in Kerman, Iran. Tropical animal health and production. 2009;41:1633-6.
  68. Agholi M, Taghadosi Z, Mehrabani D, Zahabiun F, Sharafi Z, Motazedian MH, et al. Human intestinal sarcocystosis in Iran: there but not seen. Parasitology research. 2016;115:4527-33.
  69. Jafari F, Motavallihaghi SM, Bakhtiari M, Maghsood AH, Foroughi-Parvar F. Sarcocystis bovifelis in raw hamburgers marketed in Hamadan City, Western Iran. Iranian Journal of Parasitology. 2022;17(1):36.
  70. Hajimohammadi B, Dehghani A, Ahmadi MM, Eslami G, Oryan A, Khamesipour A. Prevalence and species identification of Sarcocystis in raw hamburgers distributed in Yazd, Iran using PCR-RFLP. J Food Qual Hazards Control. 2014;1(1):15-20.
  71. Faghiri E, Davari A, Nabavi R. Histopathological Survey on Sarcocystis Species Infection in Slaughtered Cattle of Zabol-Iran/Zabol-Iran'da Kesilen Sigirlarda Sarcocystis Turlerinin Yol Actigi Enfeksiyonlar Uzerine Histopatolojik Inceleme. Turkish Journal of Parasitology. 2019;43(4):182-7.
  72. Rahdar M, Salehi M. The prevalence of Sarcocystis infection in meat-production by using digestion method in Ahvaz, Iran. 2011.
  73. Firoozi Z, Sazmand A, Zahedi A, Astani A, Fattahi-Bafghi A, Kiani-Salmi N, et al. Prevalence and genotyping identification of Cryptosporidium in adult ruminants in central Iran. Parasites & vectors. 2019;12:1-6.
  74. Bafghi AF, Yavari MR, Mirzaei F, Siyadatpanah A, Mitsuwan W, de Lourdes Pereira M, et al. Prevalence and risk factors associated with cryptosporidium infection in raw vegetables in Yazd District, Iran. World. 2020;10(3):260-6.
  75. Gurunathan K, Babji Y. 19 Meat-borne zoonotic diseases and their prevention. Recent Approaches to Contain the Global Zoonotic Burden.150.
  76. Constable P. Hinchcliff ٴ, KW, Done SH, Grundberg W. Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs, and Goats. 2017.
  77. Zahedi A, Ryan U. Cryptosporidium–an update with an emphasis on foodborne and waterborne transmission. Research in Veterinary Science. 2020;132:500-12.
  78. McEvoy J, Duffy G, Moriarty E, Lowery C, Sheridan J, Blair I, et al. The prevalence and characterisation of Cryptosporidium spp. in beef abattoir water supplies. Water research. 2005;39(15):3697-703.
  79. Zangeneh M, Banaeian N, Clark S. Meta-analysis on energy-use patterns of cropping systems in Iran. Sustainability. 2021;13(7):3868.

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History

  • Receive Date: 16 June 2024
  • Revise Date: 24 August 2024
  • Accept Date: 27 August 2024

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