Advancement in Electrochemical DNA-biosensors for GMOs Detection: A review

Document Type: Review Article


1 Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Nutritional Sciences Department, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.

3 Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences (MUMS), Paradise Daneshgah, Azadi Square, Mashad, Iran

4 Department of Health Education and Health Promotion, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

5 Medical School, University of Aberdeen, Foresterhill, Aberdeen, UK.


Genetically modified organisms (GMOs) are plants or animals whose genetic make-up has been transformed by recombinant DNA technology, which has new features such as resistance to herbicides, virus and insect. Recently, genetic modification of food products has increased in order to reduce world poverty and hunger and increase food production However, the impact of GMOs on the human health is a growing concern worldwide. Due to increased global production of GMOs, the presence of these in food products need to be monitored and has been attended by many researchers recently. The quick, simple, accurate and sensitive detection methods for these products have attracted the attention. Electrochemical DNA biosensors as one of these fast methods are highly studied by many researchers due to their high sensitivity, low cost, rapid reaction and the possibility of working in aqueous solutions. The present review will focus on several studies on the detection of GMO based on electrochemical biosensors.


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