Relationship between Anthropometric Parameters and Hepatic Steatosis

Document Type: Research Paper

Authors

1 Student Research Committee, Faculty of Medicine, Islamic Azad University, Mashhad branch, Mashhad, Iran

2 Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

4 Department of nutrition, School of Nutrition science and food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran

5 Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

6 Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

7 Department of Pediatric Gastroenterology, Mashhad University of Medical Sciences, Mashhad, Iran

8 Department of Biostatistics and Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

9 Department of Nutrition, School of Medicine, Biochemistry and Nutrition, Endoscopic & Minimally Invasive Surgery, and Cancer Research Centers, Mashhad University of Medical Sciences (MUMS), Paradise Daneshgah, Azadi Square, Mashad, Iran

Abstract

Introduction: Non-alcoholic fatty liver disease (NAFLD) is an important health problem globally that characterized as a disease spectrum which includes simple steatosis, non-alcoholic steatohepatitis and liver fibrosis and cirrhosis. The prevalence of NAFLD has significantly increased recently. The aim of this study was to investigate the relationship between anthropometric parameters and hepatic steatosis.Methods: This cross-sectional study was performed on 415 eligible participants. Anthropometric parameters were evaluated by standard methods and fat mass was measured with bioelectrical impedance analysis. Hepatic steatosis was diagnosed using FibroScan.Results: Of the 415 participants, 308 (74.2%) had hepatic steatosis. Body mass index and waist circumference were significantly higher in patients with hepatic steatosis.  Hepatic steatosis had a significant and positive association with WC, body fat mass, and trunk fat mass. The trunk fat mass had the highest association with hepatic steatosis.  Conclusion: The present study demonstrated that anthropometric measurements are related to increase hepatic steatosis even after adjustment for age and weight. 

Keywords


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Articles in Press, Accepted Manuscript
Available Online from 03 July 2019
  • Receive Date: 29 June 2019
  • Accept Date: 03 July 2019