Document Type: Short Communication
Faculty of pharmacy, Mashhad University of Medical Sciences. Mashhad, Iran
Biochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Key State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, ChineseAcademy of Sciences, Chaoyang, Beijing, China
Introduction: we conducted this study to investigate the role of Ramadan fasting on oxidative stress. Method: 23 people (16 male, 7 female) aged between 25 and 65 years were recruited in this study. 10cc Venous blood samples were taken after 8- to 10- hours fasting on 2 different times: a week before Ramadan and at the end of Ramadan (day 27). Portions of the serum samples were used immediately to measure prooxidant-antioxidant balance (PAB). Results: the changes of oxidative stress was not significant in control group. Moreover, these changes also were non-significant in both gender. Oxidative stress was significantly increase in patients with CAD during Ramadan fasting. Conclusion: It seems that Ramadan fasting does not affect oxidative and prooxidant-antioxidant balance meaningfully. However, more studies are required in this field.