Effects of Ramadan Fasting on Oxidative Stress and Prooxidant-antioxidant Balance: A Short Communication

Document Type : Short Communication

Authors

1 Faculty of pharmacy, Mashhad University of Medical Sciences. Mashhad, Iran

2 Biochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 Key State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, ChineseAcademy of Sciences, Chaoyang, Beijing, China

Abstract

Introduction: we conducted this study to investigate the role of Ramadan fasting on oxidative stress. Method: 23 people (16 male, 7 female) aged between 25 and 65 years were recruited in this study. 10cc Venous blood samples were taken after 8- to 10- hours fasting on 2 different times: a week before Ramadan and at the end of Ramadan (day 27). Portions of the serum samples were used immediately to measure prooxidant-antioxidant balance (PAB). Results: the changes of oxidative stress was not significant in control group. Moreover, these changes also were non-significant in both gender. Oxidative stress was significantly increase in patients with CAD during Ramadan fasting. Conclusion: It seems that Ramadan fasting does not affect oxidative and prooxidant-antioxidant balance meaningfully. However, more studies are required in this field.

Keywords

References

  1. Sadiya A, Ahmed S, Siddieg HH, Babas IJ, Carlsson M. Effect of Ramadan fasting on metabolic markers, body composition, and dietary intake in Emiratis of Ajman (UAE) with metabolic syndrome. Diabetes Metab Syndr Obes. 2011; 4:409-16.
  2. Mazidi M, Rezaie P, Nematy M. The effects of Ramadan fasting on growth parameters: A narrative review. J Fasting Health. 2014; 2(1):41-5.
  3. Nematy M, Alinezhad-Namaghi M, Rashed MM, Mozhdehifard M, Sajjadi SS, Akhlaghi S, et al. Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study. Nutr J. 2012; 11:69.
  4. Chandra K, Salman AS, Mohd A, Sweety R, Ali KN. Protection against FCA induced oxidative stress induced DNA damage as a model of arthritis and In vitro anti-arthritic potential of costus speciosus rhizome extract. Inter J Pharma Phyto Res. 2015; 7(2):383-9.
  5. Rahsepar AA, Pourghadamyari H, Moohebati M, Parizadeh SM, Tavallaie S, Paydar R, et al. Prooxidant–anti-oxidant balance is not associated with extent of coronary artery disease. Clin Biochem. 2011; 44(16):1304-8.
  6. Nematy M, Alinezhad-Namaghi M, Rashed MM, Mozhdehifard M, Sajjadi SS, Akhlaghi S, et al. Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study. Nutr J. 2012; 11:69.
  7. Ibrahim WH, Habib HM, Jarrar AH, Al Baz SA. Effect of Ramadan fasting on markers of oxidative stress and serum biochemical markers of cellular damage in healthy subjects. Ann Nutr Metab. 2008; 53(3-4):175-81.
  8. Ozturk E, Balat O, Ugur MG, Yazıcıoglu C, Pence S, Erel Ö, et al. Effect of Ramadan fasting on maternal oxidative stress during the second trimester: A preliminary study. J Obstet Gynaecol Res. 2011; 37(7):729-33.
  9. Al-Shafei AI. Ramadan fasting ameliorates arterial pulse pressure and lipid profile, and alleviates oxidative stress in hypertensive patients. Blood Press. 2014; 23(3):160-7.
  10. Salahuddin M, Javed MUH. Effects of Ramadan fasting on some physiological and biochemical parameters in healthy and hypertensive subjects in Aurangabad district of Maharashtra, India. J Fasting Health. 2014; 2(1):7-13.
  11. Faris MA, Hussein RN, Al-Kurd RA, Al-Fararjeh MA, Bustanji YK, Mohammad MK. Impact of ramadan intermittent fasting on oxidative stress measured by urinary 15-f(2t)-isoprostane. J Nutr Metab. 2012; 2012:802924.

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History

  • Receive Date: 09 June 2015
  • Revise Date: 23 June 2015
  • Accept Date: 28 June 2015

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