Anatomical Distribution and Demographic Data of Gastric Cancer in Mashhad, Iran

Document Type : Letter to the Editor


1 Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 Department of Psychiatry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 Gastric Cancer Research Group, Mashhad University of Medical Sciences, Mashhad, Iran

5 Department of internal medicine, Qaem hospital, Mashhad University of Medical Sciences, Mashhad, Iran


Introduction: The global incidence of gastric cancer (GC) has been decreased dramatically in recent decades and characteristics of this cancer has been changed. Most of these changes can be resulted from changes in dietary and nutritional habits. This cancer is the most common cancer in north and northeast of Iran. In present report we will briefly summaries the gastric tumor location in a population from north east of Iran. Methods: We have evaluated the stomach tumors location according to patient’s gender and age. Among 212 Iranian patients who were lived in Mashhad, Iran, the cardia was the most common involved anatomic location. There wasn’t any significant relation between patient gender and tumor location as well as patient age and tumor location. Results: According to our results, the incidence of gastric cancer in patients who are aged between 60 to 69 years is decreasing in our population while the most common anatomic site of tumor remains the same. Conclusion: By knowing the most prevalent tumor site and related risk factors, more precise diagnostic and preventing programs can be established. Increasing global awareness about the risk factors of GC seems to be the main reason and efforts should be made to speed up this issue.


1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA: a cancer journal for clinicians. 2016;66(1):7-30.
2. Torre LA, Sauer AMG, Chen MS, Kagawa‐Singer M, Jemal A, Siegel RL. Cancer statistics for Asian Americans, Native Hawaiians, and Pacific Islanders, 2016: Converging incidence in males and females. CA: a cancer journal for clinicians. 2016;66(3):182-202.
3. Pesic M, Karanikolic A, Djordjevic N, Vuka K, Rancic Z, Radojković M, et al. The importance of primary gastric cancer location in 5-year survival rate2004. 51-3 p.
4. Malekzadeh R, Derakhshan MH, Malekzadeh Z. Gastric cancer in Iran: epidemiology and risk factors. Archives of Iranian medicine. 2009;12(6):576-83.
5. Nourozinia F, Rasmi Y, Otarod M, Golizadeh M, Khadem-Ansari M-H. Epidemiology and histopathology of gastric cancer in Urmia. URMIA MEDICAL JOURNAL. 2013;24(3):170-5.
6. Norouzinia M, Asadzadeh H, Shalmani HM, Al Dulaimi D, Zali M. Clinical and histological indicators of proximal and distal gastric cancer in eight provinces of Iran. Asian Pacific Journal of Cancer Prevention. 2012;13(11):5677-9.
7. Sardarinia M, Akbarpour S, Lotfaliany M, Bagherzadeh-Khiabani F, Bozorgmanesh M, Sheikholeslami F, et al. Risk Factors for Incidence of Cardiovascular Diseases and All-Cause Mortality in a Middle Eastern Population over a Decade Follow-up: Tehran Lipid and Glucose Study. PloS one. 2016;11(12):e0167623.