Journal of Nutrition,Fasting and Health

Journal of Nutrition,Fasting and Health

Effects of Ramadan Fasting on Ambulatory Blood Pressure in Hypertensive Patients

Document Type : Research Paper

Authors
Maryam Alinezhad Namaghi 1
Mahdi Hasanzadeh Dalooe 2
Amir Hosein Khoshnasab 2
Mohsen Nematy 3
Adeleh Khoshnasab 4
Javad Farrokhi 5
Abdolreza Norouzy 1
1 Biochemistry and Nutrition Research Center and Department of Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
2 Department of Cardiology, Ghaem Teaching Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Nutrition, School of Medicine, Biochemistry and Nutrition, Endoscopic & Minimally Invasive Surgery, and Cancer Research Center, Mashhad University of Medical Sciences, University Paradise, Azadi Square, Mashhad, Iran
4 Baqiyatallah University of Medical Sciences, Tehran, Iran
5 University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
10.22038/jfh.2014.2250
Abstract
Introduction: Previous studies have indicated that Ramadan fasting has beneficial effects on cardiovascular risk factors, specially blood pressure and heart rate. In the present study, the effect of Ramadan fasting on 24-hour ambulatory blood pressure and heart rate has been investigated. Methods: This prospective observational study was conducted on two groups of individuals. Six patients under hypertension treatment were allocated to the case group and 12 healthy individuals were selected as the control group. Twenty-four-hour blood pressure monitoring was carried out during four periods: prior to Ramadan, during the first ten days and the last ten days of Ramadan, and one month after it. All patients continued their medication, which was administered twice per day. Twenty-four-hour mean blood pressure, weight, body mass index (BMI), and waist circumference were compared among the groups. Results: In the case group, there was a significant reduction in subjects’ weight during the third period of the experiment; also, a significant improvement was observed in the heart rate during the second and third periods in the case group (P<0.05, t-test). Conclusion: This study indicated a significant improvement in the subjects’ heart rate over second and third periods of measurements; also, no high-risk variations in blood pressure or heart rate were observed among the subjects.
Keywords
Ramadan fasting
Ambulatory blood pressure
Hypertensive patients
  1. Nematy M, inezhad-Namaghi M, Rashed MM, Mozhdehifard M, Sajjadi SS, Akhlaghi S, et al. Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study. Nutr J 2012;11:69.
  2. WHO. The global burden of disease: 2004 update. THE REPORT IN SECTIONS. Part 2: Causes of death. Internet: http://www.who.int/healthinfo/global_burden_disease/2004_report_update/en/index.html. (accessed 11November 2009). 2009.
  3. Sarraf-Zadegan N, Boshtam M, Rafiei M. Risk factors for coronary artery disease in Isfahan, Iran. European Journal of Public Health 1999;9(1):20-6.
  4. Perk G, Ghanem J, Aamar S, Ben-Ishay D, Bursztyn M. The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives. J Hum Hypertens 2001 Oct;15(10):723-5.
  5. Ural E, Kozdag G, Kilic T, Ural D, Sahin T, Celebi O, et al. The effect of Ramadan fasting on ambulatory blood pressure in hypertensive patients using combination drug therapy. J Hum Hypertens 2008 Mar;22(3):208-10.
  6. Palatini P, Mormino P, Canali C, Santonastaso M, De VG, Zanata G, et al. Factors affecting ambulatory blood pressure reproducibility. Results of the HARVEST Trial. Hypertension and Ambulatory Recording Venetia Study. Hypertension 1994 Feb;23(2):211-6.
  7. Perk G, Ghanem J, Aamar S, Ben-Ishay D, Bursztyn M. The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives. J Hum Hypertens 2001 Oct;15(10):723-5.
  8. Habbal R, Azzouzi L, Adnan K, Tahiri A, Chraibi N. [Variations of blood pressure during the month of Ramadan]. Arch Mal Coeur Vaiss 1998 Aug;91(8):995-8.
  9. Adlouni A, Ghalim N, Benslimane A, Lecerf JM, Saile R. Fasting during Ramadan induces a marked increase in high-density lipoprotein cholesterol and decrease in low-density lipoprotein cholesterol. Ann Nutr Metab 1997;41(4):242-9.
  10. Khatib FA, Shafagoj YA. Metabolic alterations as a result of Ramadan fasting in non-insulin-dependent diabetes mellitus patients in relation to food intake. Saudi Med J 2004 Dec;25(12):1858-63.
  11. Yucel A, Degirmenci B, Acar M, Albayrak R, Haktanir A. The effect of fasting month of Ramadan on the abdominal fat distribution: assessment by computed tomography. Tohoku J Exp Med 2004 Nov;204(3):179-87.
  12. Aybak M, Turkoglu A, Sermet A, Denli O. Effect of Ramadan fasting on platelet aggregation in healthy male subjects. Eur J Appl Physiol Occup Physiol 1996;73(6):552-6.

  • Receive Date 23 January 2014
  • Revise Date 28 January 2014
  • Accept Date 29 January 2014