Association of Covid-19 Infection with Physical Activity and Food Intake; Mashhad PERSIAN Cohort Results

Document Type : Research Paper


1 Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Department of Nutrition, North Khorasan University of Medical Sciences, Bojnourd, Iran.

3 Department of Community Medicine, Clinical Research Development Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Department of Medical Informatics, Pharmacy School, Mashhad University of Medical Sciences, Mashhad, Iran.

5 International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


Introduction: The emergence of the COVID-19 pandemic in December 2019 had a profound impact on global public health. This study investigates the effects of the coronavirus on dietary intake and physical activity among the Mashhad PERSIAN cohort population in Mashhad, Iran. Method: This nested cohort study was done among the PERSIAN Cohort Study in Mashhad University of Medical Sciences population who confirmed COVID-19 infection through PCR testing. Participants were assessed for physical activity using the International Physical Activity Questionnaire (IPAQ) short form, as well as changes in appetite and food intake during the COVID-19 infection. All measurements were compared during the disease period to pre-infection. Results: This study comprised 381 confirmed COVID-19 patients (average age of 42.51 ± 7.31 years) of which 154 (40.4%) were male. There was a significant reduction in the levels of vigorous and moderate physical activity, walking, and total sitting time (P<0.001 for all). Also, food intake was reduced during the COVID-19 infection compared to before the infection. Conclusion: In summary, this study demonstrates a significant decrease in physical activity and food intake during COVID-19 infection. 


Main Subjects

  1. Rabi FA, Al Zoubi MS, Kasasbeh GA, Salameh DM, Al-Nasser AD. SARS-CoV-2 and coronavirus disease 2019: what we know so far. Pathogens. 2020;9(3):231.
  2. R Ruiz-Roso MB, de Carvalho Padilha P, Mantilla-Escalante DC, Ulloa N, Brun P, Acevedo-Correa D, Arantes Ferreira Peres W, Martorell M, Aires MT, de Oliveira Cardoso L, Carrasco-Marín F. Covid-19 confinement and changes of adolescent’s dietary trends in Italy, Spain, Chile, Colombia and Brazil. Nutrients. 2020;12(6):1807.
  3. Lana RM, Coelho FC, Gomes M, Cruz OG, Bastos LS, Villela DAM, et al. The novel coronavirus (SARS-CoV-2) emergency and the role of timely and effective national health surveillance. Cad Saude Publica. 2020;36(3):e00019620.
  4. Muscogiuri G, Barrea L, Savastano S, Colao A. Nutritional recommendations for CoVID-19 quarantine. Eur J Clin Nutr. 2020;74(6):850-1.
  5. Brooks SK, Webster RK, Smith LE, Woodland L, Wessely S, Greenberg N, et al. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet. 2020;395(10227):912-20.
  6. Hawryluck L, Gold WL, Robinson S, Pogorski S, Galea S, Styra R. SARS control and psychological effects of quarantine, Toronto, Canada. Emerg Infect Dis. 2004;10(7):1206-12.
  7. Johal SS. Psychosocial impacts of quarantine during disease outbreaks and interventions that may help to relieve strain. N Z Med J. 2009;122(1296): 52-47.
  8. Jeong H, Yim HW, Song YJ, Ki M, Min JA, Cho J, et al. Mental health status of people isolated due to Middle East Respiratory Syndrome. Epidemiol Health. 2016;38:e2016048.
  9. Tomova L, Wang KL, Thompson T, Matthews GA, Takahashi A, Tye KM, et al. Acute social isolation evokes midbrain craving responses similar to hunger. Nat Neurosci. 2020;23(12):1597-605.
  10. Antunes R, Frontini R, Amaro N, Salvador R, Matos R, Morouço P, Rebelo-Gonçalves R. Exploring lifestyle habits, physical activity, anxiety and basic psychological needs in a sample of Portuguese adults during COVID-19. Int J Environ Res Public Health. 2020;17(12):4360.
  11. Sinha M, Pande B, Sinha R. Impact of COVID-19 lockdown on sleep-wake schedule and associated lifestyle related behavior: A national survey. J Public Health Res. 2020;9(3):1826.
  12. Tohidinezhad F, Khorsand A, Zakavi SR, Rezvani R, Zarei-Ghanavati S, Abrishami M, Moradi A, Tavakoli M, Farrokh D, Rad MP, Abbasi B. The burden and predisposing factors of non-communicable diseases in Mashhad University of Medical Sciences personnel: a prospective 15-year organizational cohort study protocol and baseline assessment. BMC Public Health. 2020 Dec;20:1-5.
  13. Craig CL, Marshall AL, Sjöström M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;35(8):1381-95.
  14. Amini H, Isanejad A, Chamani N, Movahedi-Fard F, Salimi F, Moezi M, et al. Physical activity during COVID-19 pandemic in the Iranian population: A brief report. Heliyon. 2020;6(11):e05411.
  15. Hazavehei SMM, Asadi Z, Hassanzadeh A, Shekarchizadeh P. Comparing the effect of two methods of presenting physical education Π course on the attitudes and practices of female Students towards regular physical activity in Isfahan University of Medical Sciences. Iranian Journal of Medical Education. 2008;8(1):121-31.
  16. Naska A, Lagiou A, Lagiou P. Dietary assessment methods in epidemiological research: current state of the art and future prospects. F1000Res. 2017;6:926.
  17. Yates T, Haffner SM, Schulte PJ, Thomas L, Huffman KM, Bales CW, et al. Association between change in daily ambulatory activity and cardiovascular events in people with impaired glucose tolerance (NAVIGATOR trial): a cohort analysis. Lancet. 2014;383(9922):1059-66.
  18. Lesser IA, Nienhuis CP. The impact of COVID-19 on physical activity behavior and well-being of Canadians. International journal of environmental research and public health. 2020;17(11):3899.
  19. Maugeri G, Castrogiovanni P, Battaglia G, Pippi R, D'Agata V, Palma A, et al. The impact of physical activity on psychological health during Covid-19 pandemic in Italy. Heliyon. 2020;6(6):e04315.
  20. Stockwell S, Trott M, Tully M, Shin J, Barnett Y, Butler L, et al. Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lockdown: a systematic review. BMJ Open Sport Exerc Med. 2021;7(1):e000960.
  21. Batlle-Bayer L, Aldaco R, Bala A, Puig R, Laso J, Margallo M, et al. Environmental and nutritional impacts of dietary changes in Spain during the COVID-19 lockdown. Sci Total Environ. 2020;748:141410.
  22. Błaszczyk-Bębenek E, Jagielski P, Bolesławska I, Jagielska A, Nitsch-Osuch A, Kawalec P. Nutrition behaviors in Polish adults before and during COVID-19 lockdown. Nutrients. 2020;12(10):3084.
  23. Jia P, Liu L, Xie X, Yuan C, Chen H, Guo B, et al. Changes in dietary patterns among youths in China during COVID-19 epidemic: The COVID-19 impact on lifestyle change survey (COINLICS). Appetite. 2021;158:105015.
  24. Larsen SC, Heitmann BL. More Frequent Intake of Regular Meals and Less Frequent Snacking Are Weakly Associated with Lower Long-Term Gains in Body Mass Index and Fat Mass in Middle-Aged Men and Women. J Nutr. 2019;149(5):824-30.
  25. Sidor A, Rzymski P. Dietary Choices and Habits during COVID-19 Lockdown: Experience from Poland. Nutrients. 2020;12(6):1657.