Journal of Nutrition,Fasting and Health

Journal of Nutrition,Fasting and Health

The Effect of Detraining Followed by Endurance Training and Salvia Officinalis supplementation on Psychological Indicators and Physiological Performance in Rats

Document Type : Research Paper

Authors
Mohammad Khalesi Haghighi
Ghobad Hassanpour
Reza Sanjariyan
Departmen of Sport Physiology, Marv.C., Islamic Azad Univercity, Marvdasht, Iran.
10.22038/jnfh.2025.81549.1524
Abstract
Introduction: This study examined the effects of two and four weeks of detraining, followed by four weeks of endurance training (ET) and Salvia officinalis (S) supplementation, on anxiety-like behaviors, aerobic capacity (AC), depression, and pain threshold (PT) in rats. Methods: In this experimental study, 40 adult female rats were randomly assigned to five groups: (1) Control, (2) Sham, (3) S, (4) ET, and (5) ETS. Rats in groups 4 and 5 underwent treadmill training for four weeks (five sessions per week, 60 minutes per session). Groups 3 and 5 received Salvia officinalis extract at 100 mg/kg/day. Data were analyzed using analysis of covariance (ANCOVA) and one-way analysis of variance (ANOVA) with repeated measures. Results: The percentage of time spent in the open arms (OA) of the elevated plus maze in the S, ET, and ETS groups was significantly higher than in the control group during both two and four weeks of detraining. However, after four weeks of detraining, this percentage was significantly lower compared to two weeks of detraining (P ≤ 0.05). No significant differences were observed in AC, depression levels, or PT between the two- and four-week detraining periods following four weeks of ET+S (P ≤ 0.05). Conclusion: The findings suggest that four weeks of Salvia officinalis supplementation and endurance training can reduce anxiety-like behaviors. However, two and four weeks of detraining may lead to an increase in anxiety-like behaviors.
Keywords
Detraining
Salvia officinalis
Anxiety
Aerobic Capacity
Depression
Pain Tolerance Threshold
Subjects
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Journal of Nutrition,Fasting and Health
Volume 13, Issue 3
Summer 2025
Pages 187-196

  • Receive Date 30 July 2024
  • Revise Date 04 January 2025
  • Accept Date 04 February 2025