Fasting Consequences during Ramadan on Lipid Profile and Dietary Patterns

Document Type : Research Paper


1 General Practitioner, Kermanshah University of Medical Sciences, Kermanshah, Iran

2 Assistant Professor in Nutrition, Nutritional Sciences Department , Kermanshah University of Medical Sciences, Kermanshah, Iran

3 Assistant Professor in Internal Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

4 Assistant Professor in Biostatistics, Kermanshah University of Medical Sciences, Kermanshah, Iran

5 BSc in Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran

6 BSc in Nutrition, Kermanshah University of Medical Sciences, Kermanshah, Iran


Introduction: The aim was to assess the effects on lifestyle and lipid profile while fasting during holy month of Ramadan. Methods: An interventional cohort study designed with 160 subjects who were fasting during Ramadan recruited from different mosques in Kermanshah. Data were collected in three stages at the beginning and at the end of Ramadan as well as one month following Ramadan using demographic and FFQ questionnaires. Blood pressure was measured and a 5 ml blood sample was collected in order to measure BUN, Creatinine, and lipid profile analysis.  Results: Significant increases was observed in total cholesterol (P=0.02), LDL-C (P=0.001), HDL-C (P=0.001), and BUN (P=0.002) following Ramadan compared with earlier measurements. Triglyceride (TG) level decreased following Ramadan (P=0.04) but returned to the same level one month later. Systolic blood pressure increased and diastolic blood pressure decreased during fasting period. There was a significant decrease in cereals, dairy products, and meat consumption while consumption of fruits and vegetables have been increased during Ramadan (P=0.003).
Conclusion: Our results revealed increased levels of T-Chol and LDL-C in fasting as well as HDL-C. Increased HDL-C may prevent the side effects of T-Chol and LDL-C in healthy subjects. Given the metabolic changes that occurred during Ramadan, healthy eating and intake of low fat and low sugar diet during Ramadan are highly recommended.


  1. Nomani M.Z.A, Hallak M.H, Nomani S, Siddiqui I.P. Changes in blood urea and glucose and their association with energy. Contaning nutrients in men on hypocaloric diet during Ramadan. Am J Clin,NUTT 1989;49:1141-45.
  2. An analysis of the world muslim population by country / region(article online).  2005.
    Ref Type: Internet Communication.
  3. Cheah SH, Ch'ng SL, Husain R, Duncan MT. Effects of fasting during Ramadan on urinary excretion in Malaysian Muslims. Br J Nutr 1990;63:329-37.
  4. Leiper JB, Molla AM, Molla AM. Effects on health of fluid restriction during fasting in Ramadan. Eur J Clin Nutr 2003;57(2):30-8.
  5. http:,www. other_day_fasting_may_reduce_cance 2012.
  6. khadija-devi. Adverse Effects of Islamic Fasting CHOWK. /74462/51533. Retrieved . http://www chowk com/ilogs 2009;74462)51533.(
  7. Ramadan.Health effects of fasting.http://www thelancet com/journals/lancet/article/PIIS0140-6736%2809%2961506-3/fulltext 2009;374(9690):588.
  8. Ramadan J, Telahoun G, Al-Zaid NS, Barac-Nieto M. Responses to,exercise, fluid and energy balances during Ramadan in sedentary and active males. Nutrition 1999;15(735):39.
  9. http:, www. dopt=Abstract&holding=npg 2012.
  10. Ziai V, Yousefi R, Ahmadinejad Z, Sheikh H, Rezaei M, Behjati MJ. The effect of ramadan fasting on serum osmolarity, some electrolytes and hematological parameters. Shahid beheshti university of medical sciences & health services endocrine & metabolism research center 2007;9(1):47-53.
  11. Saleh Mansi KM. Study the Effects of Ramadan Fasting on the Serum Glucose andLipid Profile among Healthy Jordanian Students. American Journal of Applied Sciences, 2007, 4 (8): 565-569.
  12. Janghorbani M. Effect of islamic fasting on body weight, blood pressure, electrolytes, blood cell count and certain serum biochemical variables in males. J Kerman university of medical sci 1995;2(4):183-92.
  13. Schemahl FW, Metzler B. The health risk of occupational stress in islamic industrial workers during the ramadan fasting period. Pol J Occup Med Environ Health 1991;4:219-28.
  14. Navaei L, Mehrabi Y, Azizi F. Changes in body weight, blood pressure, consumption pattern and biochemical parameters in diabetic patients during fasting in Ramadan. Iranian Journal of Endocrinology and Metabolism 2001;3(2):125-32.
  15. Sajid KM,Aktar M,Malia GO.Ramadan fasting and thyroid hormone profile.JPMA 1991;41(213):216.
  16. Sadiya A, Ahmed S, Siddieg HH, Babas IJ, Carlsson M. Effect of Ramadan fasting on metabolic markers, body composition, and dietary intake in Emiratis of Ajman (UAE) with metabolic syndrome. Diabetes Metab Syndr Obes 2011;4:409-16.
  17. Arthur L, Francisco J, Smith K. The pathogenesis of obesity. Clin Endo and Met 1999;13(1):13-30.
  18. Wolf  A, Colditz G. Current estimates of the economic cost of obesity in the United States. Obes Res 1998;6:97-106.
  19. Al-Nuaim A. . prevalence of diabetes mellitus, obesity and hypercholesterolemia in Saudi Arabia. In: Musaiger AO , ilady SS , editors . diet-related non-communicable diseases in the arab countries of the gulf. Cairo 1996;73-81.
  20. Musaiger AO. Trends in diet- related chronic diseases in united arab emirates. In: Musaiger AO , ilady SS , editors . diet-related non-communicable diseases in the arab countries of the gulf.  FAO; 1996. Report No.: 73-81.
  21. al-Isa AN. Prevalence of  obesity among adult Kuwaitis: a cross-sectional study. Obes relat metab disord 1995; 19:431-3.
  22. al-Mannai  A, Dickerson J, Morgan J, Khalfan H.  Obesity in Bahraini. R Soc Health 1996;116;30(2)37-40. 
  23. Asgari S, Aghaei A, Naderi Gh, Azali Sh. The inhibitory effect of fasting on lipid peroxidation;A protective role on cardiovascular system. The Journal of Qazvin Univ of Med Sci 2005;9(34):13-7.
  24. Adlouni A, Ghalim N, Benslimane A, Lecert JM, Saile R. Fasting during Ramadan induces a marked increase in high-density lipoprotein cholesterol and decrease in low-density lipoprotein cholesterol. Ann Nutr Metab 1997;41(4):242-9.
  25. Hallak MH, Nomani MZ. Body weight loss and changes in blood lipid levels in normal men on hypocaloric diets during Ramadan fasting. Am J Clin Nutr 1998;48(5):1197-210.
  26. Babaee A.K, Ghasemi M, Tavakili H, Yoosefi A. Study of some biochemical parameters in male university students affected by Ramadan fasting. J university Khorasan shomali medical sci 2008;1(1):21-6.
  27. Azizi F, Amir Rasouli HA. Serum glocose,bilirubin,calcium,phosphorus,protein and albumin concentrations during Ramadan. Med J IRI 1987;1:38-41.
  28. Owen PE. Starvation In: DeGroot LJ(ed). Endocrinology 2nd edi Philadelphia Saunders 1989;3:2282-93.
  29. Scott TG. The effect of muslim fast of Ramadan on routine laboratory investigation. King Abdolaziz Med J 1981;1:23-35.
  30. Soulaiman AN, Elkhatib FA. Effect of fasting during Ramadan on weight and some blood constitiuents in healthy muslims.In the first international congress on healths and Ramadan Casablanca. Morocco 1994.
  31. Yarahmadi S, Larijani B, Bastanhagh MH, Pajouhi M, Baradar JR, Zahedi F, et al. Metabolic and clinical effects of Ramadan fasting in patients with type II diabetes. J Coll Physicians Surg Pak 2003 Jun;13(6):329-32.
  32. Zareh M M GhR. Study of some biochemical parameters in male university students affected by Ramadan fasting. J Sabzevar university of medical sci 2002;9(3):30-5.
  33. Dewanti L, Watanabe C, Sulistiawati, Ohtsuka R. Unexpected changes in blood pressure and hematological parameters among fasting and nonfasting workers during Ramadan in Indonesia. Eur J Clin Nutr 2006 Jul;60(7):877-81.
  34. Sarraf-Zadegan N, Atashi M, Naderi GA, Baghai AM, Asgary S, Fatehifar MR, et al. The effect of fasting in Ramadan on the values and interrelations between biochemical, coagulation and hematological factors. Ann Saudi Med 2000;20:377-81.
  35. Fakhrzadeh H, Larijani B, Sanjari M, Baradar-Jalili R, Amini MR. Effect of Ramadan fasting on clinical and biochemical parameters in healthy adults. Ann Saudi Med 2003;23:223-6.
  36. Ramadan J. Does fasting during Ramadan alter body composition, blood constituents and physical performance? Med Princ Pract 2002;11(2):41-6.
  37. Trepanowski JF, Bloomer RJ. The impact of religious fasting on human health. Nutr J 2010;9:57.
  38. Kassab S, bdul-Ghaffar T, Nagalla DS, Sachdeva U, Nayar U. Interactions between leptin, neuropeptide-Y and insulin with chronic diurnal fasting during Ramadan. Ann Saudi Med 2004 Sep;24(5):345-9.
  39. Adair LS. Dramatic rise in overweight and obesity in adult Filipino women and risk of hypertension. Obes Res 2004;12:1335-41.
  40. Capuano V, Bambacaro A, D'Arminio T, Vecchio G, Cappuccio L. Correlation between body mass index and others risk factors for cardiovascular disease in women compared with men. Monaldi Arch Chest Dis 2003;60(295):300.
  41. Reisin E, Abel R, Modan M, Silverberg DS, Eliahon HE, Modan B. Effects of weight loss without salt restriction on the reduction of blood pressure in overweight hypertensive patients. N Engl J Med 1978;298:1-6.
  42. Saleh SA, El-Kemery TA, Farrag KA, Badawy MR, Sarkis NN, Soliman FS, et al. Ramadan fasting: relation to atherogenic risk among obese Muslims. J Egypt Public Health Assoc 2004;79(5-6):461-83.
  43. Wissam HI, Hosam MH, Amjad HJ, Samer AAB. Effect of Ramadan fasting on markers of oxidative stress and serum biochemical markers of cellular damage in healthy subjects. Ann Nutr Metab 2008;53(175):181.