Journal of Nutrition,Fasting and Health

Journal of Nutrition,Fasting and Health

The Effects of Ramadan Fasting on the Level of Sex Hormones in Pre-menarche Girls in Mashhad, Iran

Document Type : Research Paper

Authors
Shohreh Bahreyni 1
Mohsen Mazidi 2
Peyman Rezaie 1
Rahim Vakili 3
Abdolreza Norouzy 1
Seyed Isaac Hashemy 4
Mahdi Ebrahimi 5
Habibolla Esmaeili 6
Payam Razavi Ebrahimi 7
Arash Akhavan-rezayat 7
Mohsen Nematy 1
1 Nutrition and Biochemistry Research Center and Department of Nutrition, Mashhad Medical School, Mashhad University of Medical Science, Iran.
2 Institute of Genetics and Developmental Biology. International College, University of Chinese Academy of Science (IC-UCAS). Beijing, China
3 Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
4 Addiction Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5 Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6 Department of Statistic, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
7 Students Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
10.22038/jfh.2015.4182
Abstract
The present study aimed to evaluate the effects of Ramadan fasting on the level of sex hormones in girls between 9-13 years before age at menarche. This study was conducted on a sample of 58 subjects (age range: 9-13 years), who were divided into two groups of fasting (N=31) and non-fasting (N=27). The levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), progesterone and estradiol were measured in all the subjects before and after Ramadan. Measurements were carried out three days before the start of Ramadan, and one day afterwards. In this study, FSH levels significantly increased in the non-fasting group (P=0.01), and the level of Dehydroepiandrostenedione (DHEA) had a significant decrease during the time of study in both groups (P=0.001, P=0.006). In addition, serum levels of LH significantly increased in the non-fasting group after Ramadan (P=0.006), and estradiol significantly increased in both groups (P=0.008, P=0.004). Given the similar changes in the levels of DHEA, progesterone and estradiol in both study groups, it could be concluded that fasting has no effects on these parameters, and the changes in LH and FSH levels could be due to other contributing factors. 
Keywords
Ramadan fasting
Pre-menarche girls
Sex hormones
Puberty
Diet
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  • Receive Date 07 March 2015
  • Revise Date 17 March 2015
  • Accept Date 19 March 2015