Journal of Nutrition,Fasting and Health

Journal of Nutrition,Fasting and Health

The Effect of Endurance Training and Purslane (Portulaca oleracea) Seed Consumption on Cytochrome- C and Malondialdehyde in the Heart Tissue of Rats Poisoned with H2O2

Document Type : Research Paper

Authors
Hamed Ariyanfar 1
Hassan Matinhomaee 1
Seyed Ali Hosseini 2
Farshad Ghazalian 3
1 Department of Sport Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
2 Department of Exercise Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
3 Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
10.22038/jnfh.2020.44729.1237
Abstract
Introduction: Oxygenated water intake can increase cell death markers by increasing free radicals; however, sport activities and antioxidant substances can prevent some symptoms of free radical production. The purpose of this study was to investigate the effect of endurance training (ET) and purslane (portulaca oleracea) seed (PO) consumption on cytochrome-C and malondialdehyde (MDA) in the heart tissue of rats poisoned with H2O2. Methods: Forty five male rats were randomly divided into 9 groups of 5 rats, including: 1)control, 2)50mg/kg PO, 3)200mg/kg PO, 4)400 mg/kg PO, 5)ET, 6)ET+50mg/kg PO, 7)ET+200mg/kg PO, 8)ET+400mg/kg PO, and 9)healthy control. During 8 weeks, groups 1-8 received 1 mmol/kg H2O2 intra-periton eally, three times per week, and groups 5-8 ran on treadmill for three days per week. Results: ET and PO significantly reduced cytochrome-C and MDA (p=0.001), however the interactive effect of ET and PO on the reduction of cytochrome-C (p=0.52) and MDA (p=0.08) was not significant; 200 mg/kg (p=0.01) and 400 mg/kg (p=0.001) PO significantly reduced cytochrome-C, as well as 400 mg/kg PO had more effect on the reduction of cytochrome-C than 200 mg/kg (p=0.01). Also, 400 mg/kg PO significantly reduced MDA (p=0.001). Conclusion: It seems that ET and PO improve cytochrome-C and MDA in the heart tissue of rats poisoned with H2O2.
Keywords
Endurance Training
Purslane Seed
Cytochrome- C
Malondialdehyde
Heart
H2O2
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Journal of Nutrition,Fasting and Health
Volume 8, Issue 2
Spring 2020
Pages 80-86

  • Receive Date 29 November 2019
  • Revise Date 12 January 2020
  • Accept Date 15 January 2020