Journal of Nutrition,Fasting and Health

Journal of Nutrition,Fasting and Health

The Comparison of Beet Juice and Ibuprofen Consumption on Muscle Damage after a Session of Resistance Exercise in Young Untrained Women

Document Type : Research Paper

Authors
Yaser Kazemzadeh 1
Melika Asgari 1
Pegah Hooshangi 2
1 Department of Sport Physiology, Faculty of Physical Education, Islamic Azad University, Eslamshahr Branch, Eslamshahr, Iran.
2 Department of Exercise Physiology, Faculty of Physical Education, Islamic Azad University, Islamshahr Branch, Islamshahr, Iran.
10.22038/jnfh.2024.80477.1517
Abstract
This study aimed to compare the consumption of two combinations of beetroot juice and ibuprofen before exercise on muscle damage indicators after a session of isotonic resistance exercise. The research samples consisted of 24 young women (20-34 years old) who were randomly divided into two groups of beetroot juice (n=12) and ibuprofen (n=12). The beet juice group received 4.5ml of natural beet juice per kilogram of body weight about 150 minutes before the activity, and the ibuprofen group received 30mg of the drug 24 hours before the activity in three meals. Both groups performed resistance activities, including six movements of the upper body and lower body in three times of 15 to 20 repetitions with 60 to 70% of the maximum strength. In the end, the levels of creatine kinase and blood myoglobin were evaluated in two stages. The data were analyzed using the independent t-test at an error level of p ≥0.05. Although the serum creatine kinase and myoglobin levels in both groups showed a significant increase compared to pre-activity (p=0.0001), no difference was observed between the groups (p=0.094 and p=0.211). In addition, the concentration of this variable in the ibuprofen consumption group had a slight change, while the increase in plasma interleukin-6 concentration in the beetroot juice consumption group had a significant increase compared to before the activity (p=0.001). The results showed that ibuprofen reduces the inflammation caused by these exercises to some extent.
Keywords
Resistance exercise
Delayed onset Muscle soreness
Beet juice
Ibuprofen
Subjects
  1. Tanabe Y, Fujii N, Suzuki K. Dietary supplementation for attenuating exercise-induced muscle damage and delayed-onset muscle soreness in humans. Nutrients. 2021; 14(1):70.
  2. Tiidus PM. Radical species in inflammation and overtraining. Canadian journal of physiology and pharmacology. 1998; 76(5):533-8.
  3. Proske U, Morgan DL. Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. The Journal of physiology. 2001; 537(2):333-45.
  4. Ji LL, Gomez-Cabrera MC, Vina J. Role of nuclear factor κ B and mitogen-activated protein kinase signaling in exercise-induced antioxidant enzyme adaptation. Applied Physiology, Nutrition, and Metabolism. 2007; 32(5):930-5.
  5. Lin CH, Lin YA, Chen SL, Hsu MC, Hsu CC. American ginseng attenuates eccentric exercise-induced muscle damage via the modulation of lipid peroxidation and inflammatory adaptation in males. Nutrients. 2021; 14(1):78.
  6. Rawson ES, Miles MP, Larson-Meyer DE. Dietary supplements for health, adaptation, and recovery in athletes. International Journal of Sport Nutrition and Exercise Metabolism. 2018; 28(2):188-99.
  7. Suzuki K, Tominaga T, Ruhee RT, Ma S. Characterization and modulation of systemic inflammatory response to exhaustive exercise in relation to oxidative stress. Antioxidants. 2020; 9(5):401.
  8. Cheung K, Hume PA, Maxwell L. Delayed onset muscle soreness: treatment strategies and performance factors. Sports medicine. 2003; 33:145-64.
  9. Nakhostin-Roohi B, Mohammadi Aghdam Z. The effect of L-Argenine supplementation on Delayed Onset Muscle Soreness (DOMS) after eccentric heavy exercise. Hormozgan Medical Journal. 2017; 21 (3): 169-177.
  10. Domínguez R, Maté-Muñoz JL, Cuenca E, García-Fernández P, Mata-Ordoñez F, Lozano-Estevan MC, Veiga-Herreros P, da Silva SF, Garnacho-Castaño MV. Effects of beetroot juice supplementation on intermittent high-intensity exercise efforts. Journal of the international society of sports nutrition. 2018; 15:1-2.
  11. Fraga GS, Aidar FJ, Matos DG, Marçal AC, Santos JL, Souza RF, Carneiro AL, Vasconcelos AB, Da Silva-Grigoletto ME, van den Tillaar R, Cabral BT. Effects of ibuprofen intake in muscle damage, body temperature and muscle power in paralympic powerlifting athletes. International journal of environmental research and public health. 2020; 17(14):5157.
  12. Jones L, Bailey SJ, Rowland SN, Alsharif N, Shannon OM, Clifford T. The effect of nitrate-rich beetroot juice on markers of exercise-induced muscle damage: A systematic review and meta-analysis of human intervention trials. Journal of Dietary Supplements. 2022; 19(6):749-71.
  13. Close GL, Ashton T, McArdle A, Maclaren DP. The emerging role of free radicals in delayed onset muscle soreness and contraction-induced muscle injury. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 2005; 142(3):257-66.
  14. Stamler JS, Meissner G. Physiology of nitric oxide in skeletal muscle. Physiological Reviews. 2001; 81(1):209-37.
  15. Bryan NS. Nitrite in nitric oxide biology: Cause or consequence?: A systems-based review. Free Radical Biology and Medicine. 2006; 41(5):691-701.
  16. Lundberg JO, Weitzberg E. NO generation from inorganic nitrate and nitrite: Role in physiology, nutrition and therapeutics. Archives of Pharmacal Research. 2009; 32:1119-26.
  17. Bryan NS, editor. Food, nutrition, and the nitric oxide pathway: biochemistry and bioactivity. DEStech Publications, Inc; 2010; 153-66.
  18. Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E. Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metabolism. 2011; 13(2):149-59.
  19. Kapil V, Milsom AB, Okorie M, et al: inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived No. Hypertension. 2010; 56:274-281.
  20. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension. 2008; 51(3):784-90.

  • Receive Date 12 June 2024
  • Revise Date 25 August 2024
  • Accept Date 27 August 2024