The Comparison of Beet Juice and Ibuprofen Consumption on Muscle Damage after a Session of Resistance Exercise in Young Untrained Women

Document Type : Research Paper

Authors

1 Assistant Professor, Department of Sport Physiology, Faculty of Physical Education, Islamic Azad University, Eslamshahr Branch, Eslamshahr, Iran.

2 Department of Sport Physiology, Faculty of Physical Education, Islamic Azad University, Eslamshahr Branch, Eslamshahr, Iran.

3 Dept. of Exercise Physiology, Faculty of Physical Education, Islamic Azad University, Islamshahr Branch, Islamshahr, Iran.

Abstract

The aim of this study was to compare the consumption of two combinations of beetroot juice and ibuprofen before exercise on muscle damage indicators after a session of isotonic resistance exercise. The samples of this research consisted of 24 young women (20-34 years old) who were randomly divided into two groups of beetroot juice (n=12) and ibuprofen (n=12). The beet juice group received 4.5 ml of natural beet juice per kilogram of body weight about 150 minutes before the activity, and the ibuprofen group received 30 mg of the drug 24 hours before the activity in three meals before the activity. they received. Both groups performed resistance activities including 6 movements of the upper body and lower body in 3 times of 15 to 20 repetitions with 60 to 70% of the maximum strength, and at the end, in two stages, the levels of creatine kinase and blood myoglobin were evaluated. The data were analyzed using the independent t-test at an error level of p ≥0.05. The results showed that although the serum creatine kinase and myoglobin levels in both groups showed a significant increase compared to pre-activity (p=0.0001), no difference was observed between the groups (p=0.094 and p=0.211). Also, while the increase in plasma interleukin-6 concentration in the beetroot juice consumption group had a significant increase compared to before the activity, the concentration of this variable in the ibuprofen consumption group had a slight change (p=0.001). These results show that ibuprofen reduces the inflammation caused by these exercises to some extent.

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Main Subjects


  1. Tanabe, Y., Fujii, N., & Suzuki, K. (2021). Dietary Supplementation for Attenuating Exercise-Induced Muscle Damage and Delayed-Onset Muscle Soreness in Humans. Nutrients14(1), 70.
  2. Tiidus, P.M. Radical species in inflammation and overtraining. Can. J. Physiol. Pharmacol. 1998, 76, 533–538. (CrossRef)
  3. Proske, U.; Morgan, D.L. Muscle damage from eccentric exercise: Mechanism, mechanical signs, adaptation and clinicalapplications. J. Physiol. 2001, 537, 333–345. (CrossRef) (PubMed)
  4. Ji, L.L.; Gomez-Cabrera, M.C.; Vina, J. Role of nuclear factor kappaB and mitogen-activated protein kinase signaling in exerciseinduced antioxidant enzyme adaptation. Appl. Physiol. Nutr. Metab. 2007, 32, 930–935. (CrossRef) (PubMed)
  5. Lin, C. H., Lin, Y. A., Chen, S. L., Hsu, M. C., & Hsu, C. C. (2021). American ginseng attenuates eccentric exercise-induced muscle damage via the modulation of lipid peroxidation and inflammatory adaptation in males. Nutrients14(1), 78.
  6. Rawson, E.S.; Miles, M.P.; Larson-Meyer, D.E. Dietary Supplements for Health, Adaptation, and Recovery in Athletes. Int. J. Sport Nutr. Exerc. Metab. 2018, 28, 188–199. (CrossRef) (PubMed)
  7. Suzuki, K.; Tominaga, T.; Ruhee, R.T.; Ma, S. Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress. Antioxidants 2020,9, 401. (CrossRef) (PubMed)
  8. Cheung, K.; Hume, P.; Maxwell, L. Delayed onset muscle soreness: Treatment strategies and performance factors. Sports Med.2003, 33, 145–164. (CrossRef) (PubMed)
  9. Nakhostin-Roohi B, Mohammadi Aghdam Z. The effect of L-Arginine supplementation on Delayed Onset Muscle Soreness (DOMS) after eccentric heavy exercise. hmj. 2017; 21 (3) :169-17
  10. Domínguez R, Maté-Muñoz JL, Cuenca E, García-Fernández P, Mata-Ordoñez F, Lozano-Estevan MC, et al. Effects of beetroot juice supplementation on intermittent high-intensity exercise efforts. J Int Soc Sports Nutr. 2018;15(1):1-12. PMID: 29311764 DOI: 10.1186/s12970-017-0204-9
  11. Fraga, G. S., Aidar, F. J., Matos, D. G., Marçal, A. C., Santos, J. L., Souza, R. F., ... & Reis, V. M. (2020). Effects of ibuprofen intake in muscle damage, body temperature and muscle power in paralympic powerlifting athletes. International journal of environmental research and public health17(14), 5157
  12. Jones, L., Bailey, S. J., Rowland, S. N., Alsharif, N., Shannon, O. M., & Clifford, T. (2021). The effect of nitrate-rich beetroot juice on markers of exercise-induced muscle damage: A systematic review and meta-analysis of human intervention trials. Journal of Dietary Supplements, 1-23.
  13. Close GL, Ashton T, McArdle A, MacLaren DP. The emerging role of free radicals in delayed onset muscle soreness and contraction-induced muscle injury. Comp Biochem Physiol A Mol Integr Physiol. 2005;142:257–266.
  14. Stamler JS, Meissner G: physiology of nitric oxide in skeletal muscle. Physio Rev 2001; 81:209-237.
  15. . Bryan NS: Nitrite in nitric oxide biology: cause or consequence? A systems-based review. Free Radic Biol Med 2006; 41:691-701.
  16. . Lundberg JO, Weitzberg E: NO generation from inorganic nitrate and nitrite: role in physiology ,nutrition and therapeutics. Arch Pharm Res2009; 32:1119-1126.
  17. Bryan NS, Hord NG: Regulations gone awry: Addressing public health concern; in Bryan NS, (ed): Food, Nutrition and the Nitric oxide pathway Pennsylvania, DEStech publication,2010, pp 153-166.
  18. . Lundberg JO, Govoni M: Inorganic nitrate is a possible source for systemic generation of nitric oxide. Free Radic Biol Med 2004; 37:395-400.
  19. . Benjamin N, O'Driscoll F, Dougall H, et al: Stomatch NO synthesis. Nature 1994; 368:502-503.
  20. . Larsen FJ, Schiffer TA, Borniquel S, et al: Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 2011; 13:149-159.
  21. . Kapil V, Milsom AB, Okorie M, et al: inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived No. Hypertension 2010;56:274-281.
  22. . Webb AJ, Patel N, Loukogeorgakis S, et al: Acute blood pressure lowering, vasoprotective, and antiplatelet properyies of dietary nitrate via bioconversion to nitrite. Hypertension 2008; 51,784-790.

Articles in Press, Accepted Manuscript
Available Online from 27 August 2024
  • Receive Date: 12 June 2024
  • Revise Date: 25 August 2024
  • Accept Date: 27 August 2024